Neonatal HSV-1 in Premature Twins Flashcards
What are the three types of neonatal HSV infections?
SEM
Encephalitis
Disseminated
Symptoms of Skin Eye Mouth (SEM) HSV
- conjuctivitis
- karatitis
- vescular lesions
Symptoms of Encephalitis HSV
- Temperature
- instability
- poor feeding
- seizures
Symptoms of Disseminated HSV
- Intravascular coagulation
- respiratory distress
- jaundice
What are the normal treatments for neonatal HSV?
IV acyclovir
What are the alternate treatments for neonatal HSV
IV Ganciclovir
IV Foscarnet
Oral Valacyvlovir
What are the three methods of contracting neonatal HSV?
invitro
intrapartum
postnatal
How do you contract HSV In utero?
Exposure to HSV virus during gestation
How do you contract HSV intrapartum
Active case of HSV acquired during birthing process
How do you contract HSV postnatal
Contact with infected caregiver
Lab data for HSV
low HCT low RBC count Blood PCR positive Viral Culture positive CSF PCR negative
HSV-1
- route of transmission
- location of lesions
- oral to oral AND oral to genital
- ulcers around the mouth
HSV-2
- route of transmission
- location of lesions
- sexual contact
- genital ulcers