Warfarin Flashcards
1
Q
How does it work?
A
Inhibiting an essential step in the synthesis of vitamin K-dependent clotting factors (II, VII, IX, and X)
2
Q
How anticoagulation measured?
A
Using PT and converting into INR
3
Q
Target INR for patient on Warfarin?
A
2-4.5
4
Q
Target INR for normal patients?
A
2-3
5
Q
Drug known to potentiate the action of warfarin?
A
Thyroxine Antibiotics (including eryhtromycin) Alcohol Anti-depressants Aspirin Amiodarone Quinine
6
Q
Rx of moderately high INR with no bleeding?
A
Omit dose of warfarin
7
Q
Rx of significantly raised INR without bleeding?
A
Omid dose of warfarin
Start vitamin K PO
8
Q
Rx of of high INR with bleeding?
A
Dose of vitamin K PO or IV
Prothrombin complex concentrate e.g. Beriplex
OR
FFP
