w/c 26/05 Flashcards
what does giving vit K to babies prevent
haemorrhagic disease of the newborn
whats foetal hyantoin syndrome
syndrome due to maternal anti epileptic use (ones which are teratogenic)
manifests as IUGR, microcephaly, cleft lip/palate, intellectual disability, hypoplastic fingernails and distal limb deformity
how many principles in the mca
5
adjustment disorder definition
clear stress
presents within 3 months of stress
sx last <6 months
what type of neonatal jaundice does hypothyroidism cause
unconjugated
NSAIDs in breastfeeding
yes
roseola infantum rash
appears after fever/coryza
starts on trunk and spreads to limbs
what do krukenberg tumors contain histologically
signet ring cells
when does vomitting in pyloric stenosis usually start
3/4th week of life
duodenal atresia is associated with
downs syndrome
describe the respiratory physiological changes in pregnancy
increased tidal volume
increased minute ventilation
this causes breathlessness
how long after vaginal PGE2 is the cervix reassessed
what is done if theres no improvement
6 hrs
if bishop score is still under 6 give PEG2 again
meckels diverticulum rule of 2s
2% of population
2cm from ileocaecal valve
2 inches long
2 types of hypertrophic mucosa (gastric or pancreatic)
how might meckels diverticula present
usually asymptomatic
may mimic appendicitis
what methods of contraception increase risk of ectopic pregnancy
POP
IUD
when is interpersonal therapy used
when there is one clear trigger that can be the focus of therapy
atypical antipsychotic starting dose
10mg
what antihypertensives can contribute to/exacerbate depression
beta blockers
what class of medication is venlaflaxine
SNRI
what class of medication is paroxetine
SSRI
what class of medication is dosulepin
tricyclic
in a second episode of depression how long should you continue antidepressants after remission
2 years
multiple episodes of mania are considered to be a diagnosis of
bipolar affective disorder
NOT recurrent mania
whats the likelihood of someone with a manic episode experiencing depression
90%
3 main effects of lithium use
hypothyroidism
nephrotoxcity
hyperparathyroidism
psychological therapy in mania
is not offered in acute phase, not really effective for mania
effective for concordance with medication and future depressive episodes
max time period of benzo use in anxiety
2-4 weeks
how should someone be weaned off benzos after long term use
reduce 1/8th dose every fortnight
what benzo has the shortest half life
lorazepam
which benzo will give the worst withdrawal sx and why
lorazepam because it has the shortest half life- switch to diazepam (longer half life) then wean off
do all adult patients who self harm need to be seen by a psychiatrist or mental health nurse before discharge?
no
use of what psychiatric medication in the first trimester is associated with cleft lip
benzodiazipines
how should women be routinely screened for depression postpartum
ask about anhedonia and low mood
if they say yes to either, use the edinburgh postnatal depression scale
knights move thinking synonym
loosening of associations
what is the treatment plan for early psychosis
start low, go slow
ie low dose antipsychotics
what are the rules around testing for huntingtons
can only be done after genetic counselling, so not by gp
huntingtons chance of passing down?
50%
environmental risk factors for alzheimers
smoking
head injury
in those with dementia how many have alzheimers
60-70%
memantine class of drug
NMDA (glutamate) receptor partial agonist
acetylcholinesterase inhibitors
donepazil
rivastigmine
galantamine
how many people recover from anorexia nervosa in 20 years
50%
main difference between anorexia nervosa and bullimia
anorexia= weight low
bullimia= wight normal
what is section 48
for transfer of an unsentenced prisoner to hospital for detention there
what is section 49
a restriction order
who can apply a section 49
ministry of justice
IQ for mild, moderate, severe and profound disability
mild= 50-69
moderate= 35-49
severe= 20-34
profound= under 20
how long does a section 5(4) last
6 hrs
what is diagnostic overshadowing
when a persons symptoms are assumed to be relating to their learning disability
why are atypical antipsychotics preferred over typical
less extra pyramidal side effects
atypical antipsychotics cause more x side effects than typicals
metabolic
antipsychotics main moa
dopamine antagonists
what things do you check before starting lithium
patient mental state
pulse/BP
FBC
TFTs
UEs
calcium
what is required before a patient can be detained under section 2?
assessment by 2 doctors
how do atypical antipsychotics cause weight gain?
increased appetite
venlaflaxine class of drug
SNRI
driving and dementia
patient should be asked to inform the DVLA (even if they can still drive)
explore accidents etc with them and the family
screening for before someone is put on an acetylcholiensterase inhibitor
peptic ulcer disease/dyspepsia
LFTs
ECG
cardiac hx
asthma
activated charcoal is given when
when a patient presents within an hour of taking an overdose
when should bloods be done in paracetamol overdose
4 hours after ingestion as this is when levels peak
when do paracetamol levels peak after overdose
4 hours
whats used in the acute treatment of mania
atypical antipsychotic
consider adding lithium or valproate
what should you not prescribe in bipolar affective disorder
antidepressant
which is the only antidepressant licensed for use in bipolar affective disorder
fluoxetine
one unit of alcohol is
the amount of alcohol an adult can metabolise in an hr, 10ml or 8g of pure ethanol
what neurotransmitter does alcohol enhance and what effect does this produce
GABA-A
causes reduced anxiety
what neurotransmitter does alcohol inhibit and what effect does this produce
NMDA
causes amnesia
harmful drinking vs dependant drinking
dependant= has withdrawal sx
harmful= non dependant drinking that continues despite harm
alchohol withdrawal time
4-12 hrs after last drink
whats the most common infection in IVDU
hep C
benzo OD reversal
flumazenil
opiate OD reversal
naloxone
when can you start buprenorphrine
when withdrawal symptoms start (dont give before this)
does opiate analgesia need to be avoided in IVDU
no
what is given acutely in delirium tremens
benzodiazepine
what medications reduce seizure threshold when giving ECT
antipsychotics
antidepressants
first rank sx of schizophrenia
auditory hallucinations (3rd person where people are speaking about pt is most common)
passivity
thought interference
delusional perception
learning disability vs difficulty
difficulty= challenges in one aspect of learning
disability= overall intellectual function is impacted
how to differentiate dilutional anaemia of pregnancy from iron deficiency anaemia
dilutional= normal MCV
IDA= microcytic
why are foreign inhaled bodies more likely to be in the right main bronchus than the left
the angle the right bronchus makes with the carina is less severe
indications for CT head within an hour in a child
do CT within an hour if more than 1 of:
- 3 episodes of vomiting
- amnesia for over 5 mins
- LOC over 5 mins
- abnormal drowsiness
- dangerous mechanism of injury
what to do if a child doesn’t qualify for CT head within an hour
observe them for 4 hrs if they have 1 of
- 3 episodes of vomiting
- amnesia for over 5 mins
- LOC over 5 mins
- abnormal drowsiness
- dangerous mechanism of injury
exudative ascites definition
> 30 g/L protein
exudative ascites causes
malignancy
abdominal TB
pancreatitis
transudate ascites definition
protein <30g/L
transudate ascites causes
cardiac failure
hypoalbunaemia
liver cirrhosis
myoexedma
renal failure
what ovarian mass is associated with meigs syndrome
ovarian fibroma
most common histological subtype of ovarian cancer
cystadenocarcinoma
corpus luteum produces what
prgesterone
what cyst is most likely to tort and why
dermoid
heavy in weight due to hair, teeth etc
usually have a long peduncle so twist anticlockwise
most common presentation of chlamydia
asymptomatic
abx for chlamydia in pregnant women
azithromycin
after CIN 1 diagnosis how often is follow up done
yearly
what diagnostic test should you not perform on an ovarian mass and why not
biopsy
it will disseminate the disease, remove the mass as a whole
how is bartholins cyst managed
marsupialisation
what class of medications are tranexamic acid and mefanamic acid
antifibrinolyitcs
in what patient group should you not discuss mirena IUS/IUD
patients who arent sexually active
what class of analgesics should be avoided in pregnancy
NSAIDs