w/c 12/02 Flashcards
what organism usually causes bronchiolitis?
RSV
what is bronchiolitis obliterans?
a complication of bronchiolitis popcorn lung- terminal bronchiolar dilation, areas of air trapping seen on CT
what causative organism usually causes bronchiolitis obliterans?
adenovirus
what is raised immune tripsinogen on heel prick suggestive of?
cystic fibrosis
what is raised phenylalanine on heel prick suggestive of?
phenylketonuria
when is the heel prick test done?
5-8 days old
how does congenital hypothyroidism present?
macroglossia
floppy baby/hypotonia
abdo distention/ constipation
umbilical distention
whats the inheritance pattern of duchennes muscular dystrophy?
x linked recessive
what is phrens sign?
does elevation of the testes relieve pain?
negative= no (seen in testicular torsion)
positive= yes (seen in epididymitis)
what organism commonly causes early onset sepsis?
group B strep
why is IgA done with anti TTG?
lack of IgA leads to false negative
medical management for TOP is recommended for what GA?
10-23+6 weeks
what types of drugs are mifepristone and misoprostol? how do they work
mifeprostone= progesterone receptor antagonist, degrades endometrium, ripens cervix, opens os etc
misoprostol- prostaglandin analogue, causes smooth muscle contraction to expel uterine contents
describe medical mx of TOP
give oral mifeprostone
give vaginal misoprostol 36-48 hrs after
what medications are given in antiphospholipid syndrome to prevent miscarriage? when are they started and how do they work
LMWH= start when foetal heartbeat detectable
low dose aspirin= start when pregnancy confirmed on urinalysis
they both prevent thrombosis
what tests are done in the combined screening test
nuchal translucency
PAPP-A
free bHCG
what is seen in the combined screening test in downs syndrome?
high nuchal translucency and b-HCG
low PAPP-A
what nerve block is performed using local for instrumental delivery?
pudendal
how often do people with HIV need cervical screening?
every year
what is given to babies when mum has hep B?
HBV IgG and HBV vaccination within 24 hrs of delivery
what age does perthes disease occur in?
4-8 yrs
what are some RF for paediatric sepsis?
break in skin (cut/burn)
immunosupression (diabetes/splenectomy/cancer treatment etc)
surgery in past 6 weeks
indwelling catheter
what is oesophageal atresia?
when the oesophagus ends blindly, failing to connect to the stomach
what are the 4 main domains of developmental milestones?
gross motor
fine motor
social
hearing and vision
what is rhesus status of mum and baby in haemolytic disease of the newborn?
mum= rhesus negative
baby= rhesus positive
how would you explain sepsis to someone?
a condition wherein the immune systems response to an infection leads to the compromise of many organs in the body, it is serious and can be lifethreatening
what ix are done in paediatric sepsis?
bedside: obs, urine dip, urine mc/s, lumbar puncture, swabs, BG
bloods: FBC, UEs, LFTs, culture, lactate VBG/ABG, CRP, clotting screen
imaging: CXR, AXR
how is sepsis in a child managed?
immediate hospital admission
administer broad spec IV abx
escalate to senior paediatrician for review within 1 hr, prepare for escalation to ITU/HDU
administer fluid bolus and maintenance fluids, high flow oxygen if needed
what is seen on bloods in women with turners syndrome?
high FSH
what drug is given in secondary nocturesis when conservative measures fail? at what age can it be given?
desmopressin
can be given to children above 7
what medication is given while awaiting surgery in babies with duct dependant lesions? whats the moa
prostaglandin E
it prevents the duct from closing
what medication should not be given while awaiting surgery in babies with duct dependant lesions? whats the moa
NSAIDs
COX inhibitors will cause the lesion to close
how is transient synovitis mx?
rest and analgesia
what type of abx are given in whopping cough? give examples
a macrolide
clarithromycin
azithromycin
what is seen on electron microscopy in minimal change disease?
diffuse effacement of foot processes on podocytes
what is meckels diverticulum and how does it present?
a congenital GI condition where there are remnants of the embryonic vitello-duct
can present with painless rectal bleeding, abdo pain etc and if obstructed more severe sx
what ix are done for meckels diverticulum?
CT
99mTC scan
how is meckels diverticulum managed?
NG decompression
surgical resection