w/c 12/02 Flashcards

1
Q

what organism usually causes bronchiolitis?

A

RSV

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2
Q

what is bronchiolitis obliterans?

A

a complication of bronchiolitis popcorn lung- terminal bronchiolar dilation, areas of air trapping seen on CT

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3
Q

what causative organism usually causes bronchiolitis obliterans?

A

adenovirus

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4
Q

what is raised immune tripsinogen on heel prick suggestive of?

A

cystic fibrosis

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5
Q

what is raised phenylalanine on heel prick suggestive of?

A

phenylketonuria

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6
Q

when is the heel prick test done?

A

5-8 days old

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7
Q

how does congenital hypothyroidism present?

A

macroglossia
floppy baby/hypotonia
abdo distention/ constipation
umbilical distention

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8
Q

whats the inheritance pattern of duchennes muscular dystrophy?

A

x linked recessive

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9
Q

what is phrens sign?

A

does elevation of the testes relieve pain?
negative= no (seen in testicular torsion)
positive= yes (seen in epididymitis)

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10
Q

what organism commonly causes early onset sepsis?

A

group B strep

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11
Q

why is IgA done with anti TTG?

A

lack of IgA leads to false negative

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12
Q

medical management for TOP is recommended for what GA?

A

10-23+6 weeks

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13
Q

what types of drugs are mifepristone and misoprostol? how do they work

A

mifeprostone= progesterone receptor antagonist, degrades endometrium, ripens cervix, opens os etc
misoprostol- prostaglandin analogue, causes smooth muscle contraction to expel uterine contents

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14
Q

describe medical mx of TOP

A

give oral mifeprostone
give vaginal misoprostol 36-48 hrs after

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15
Q

what medications are given in antiphospholipid syndrome to prevent miscarriage? when are they started and how do they work

A

LMWH= start when foetal heartbeat detectable
low dose aspirin= start when pregnancy confirmed on urinalysis
they both prevent thrombosis

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16
Q

what tests are done in the combined screening test

A

nuchal translucency
PAPP-A
free bHCG

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17
Q

what is seen in the combined screening test in downs syndrome?

A

high nuchal translucency and b-HCG
low PAPP-A

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18
Q

what nerve block is performed using local for instrumental delivery?

A

pudendal

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19
Q

how often do people with HIV need cervical screening?

A

every year

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20
Q

what is given to babies when mum has hep B?

A

HBV IgG and HBV vaccination within 24 hrs of delivery

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21
Q

what age does perthes disease occur in?

A

4-8 yrs

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22
Q

what are some RF for paediatric sepsis?

A

break in skin (cut/burn)
immunosupression (diabetes/splenectomy/cancer treatment etc)
surgery in past 6 weeks
indwelling catheter

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23
Q

what is oesophageal atresia?

A

when the oesophagus ends blindly, failing to connect to the stomach

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24
Q

what are the 4 main domains of developmental milestones?

A

gross motor
fine motor
social
hearing and vision

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25
Q

what is rhesus status of mum and baby in haemolytic disease of the newborn?

A

mum= rhesus negative
baby= rhesus positive

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26
Q

how would you explain sepsis to someone?

A

a condition wherein the immune systems response to an infection leads to the compromise of many organs in the body, it is serious and can be lifethreatening

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27
Q

what ix are done in paediatric sepsis?

A

bedside: obs, urine dip, urine mc/s, lumbar puncture, swabs, BG
bloods: FBC, UEs, LFTs, culture, lactate VBG/ABG, CRP, clotting screen
imaging: CXR, AXR

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28
Q

how is sepsis in a child managed?

A

immediate hospital admission
administer broad spec IV abx
escalate to senior paediatrician for review within 1 hr, prepare for escalation to ITU/HDU
administer fluid bolus and maintenance fluids, high flow oxygen if needed

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29
Q

what is seen on bloods in women with turners syndrome?

A

high FSH

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30
Q

what drug is given in secondary nocturesis when conservative measures fail? at what age can it be given?

A

desmopressin
can be given to children above 7

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31
Q

what medication is given while awaiting surgery in babies with duct dependant lesions? whats the moa

A

prostaglandin E
it prevents the duct from closing

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32
Q

what medication should not be given while awaiting surgery in babies with duct dependant lesions? whats the moa

A

NSAIDs
COX inhibitors will cause the lesion to close

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33
Q

how is transient synovitis mx?

A

rest and analgesia

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34
Q

what type of abx are given in whopping cough? give examples

A

a macrolide
clarithromycin
azithromycin

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35
Q

what is seen on electron microscopy in minimal change disease?

A

diffuse effacement of foot processes on podocytes

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36
Q

what is meckels diverticulum and how does it present?

A

a congenital GI condition where there are remnants of the embryonic vitello-duct

can present with painless rectal bleeding, abdo pain etc and if obstructed more severe sx

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37
Q

what ix are done for meckels diverticulum?

A

CT
99mTC scan

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38
Q

how is meckels diverticulum managed?

A

NG decompression
surgical resection

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39
Q

how is bilirubin measured in babies with jaundice first?

A

transcutaneous

40
Q

what are the other names for slapped cheek syndrome?

A

erythema infectiosum
fifth disease

41
Q

what age is premature ovarian insufficiency diagnosed in?

A

under 40

42
Q

what does a positive coombs test in a newborn baby confirm?

A

immune mediated haemolytic anaemia (rhesus disease)

43
Q

what medication regime is adopted in pregnant women with hypothyroidism?

A

increase levothyroxine by 25mcg daily even if the patient is euthyroid

44
Q

whats the most common type of vulval cancer?

A

squamous cell carcinoma

45
Q

in cervical ectropion what type of cell extends to where?

A

ectopic columnar epithelium extends from the endocervix to the ectocervix

46
Q

what HRT is recommend for perimenopausal vs most menopausal women? say how they differ

A

perimenopausal: monthly cyclical HRT where oestrogen is given always and progestogen last 10-14 days, induces a withdrawal bleed in final phase

postmenopausal: continuous combined HRT where oestrogen and progestogen are taken daily to mimic the effects of physiological menopause

47
Q

how do you differentiate pre eclampsia from pregnancy associated htn?

A

pre eclampsia= proteinuria present, >140 systolic and/or >90 diastolic

48
Q

list RF of ectopic pregnancy

A

endometriosis
PID
smoking
IVF
previous ectopic
age over 35

49
Q

whats the biggest risk with IOL for a healthy women who hasnt gone into labour on time?

A

failure of induction and c section required

50
Q

what is given in paracetamol overdose

A

n acetylcystine

51
Q

what is significant paracetamol overdose?

A

> 75mg/kg

52
Q

how is delirium managed

A

de escalation techniques
IM haloperidol

53
Q

how long does section 5(2) last?

A

72 hrs

54
Q

what are common side effects of SSRI in first 2 weeks?

A

GI disturbance
agitation
increased anxiety

55
Q

whats the difference between schizoid vs schizotypal personality disorder?

A

schizoid= detachment from social relationships and emotional withdrawal
schizotypal= magical/strange beliefs

56
Q

what are class a personality disorders?

A

paranoid
schizoid
schizotypal

57
Q

what blood test is done for biliary atresia and what is seen?

A

serum total and conjugated bilirubin
both are high

58
Q

what organism commonly causes croup?

A

parainfluenza

59
Q

what are hyperinflated lungs and fluid level in a newborn characteristic of?

A

transient tachypnoea of the newborn

60
Q

what conditions are those with downs syndrome at risk of developing?

A

ALL
Alzheimers

61
Q

what differetiates oligoarticular vs polyarticular juvenile idiopathi arthritis?

A

oligo= four or fewer joints
poly= more than four

62
Q

how is oligoarticular polyarticular juvenile idiopathic arthritis managed?

A

intraarticular steroids

63
Q

what is seen on xray in someone with ewings sarcoma?

A

lamellated (onion skin) periosteal reaction

64
Q

what is seen on mri in someone with ewings sarcoma?

A

a large mass with evidence of necrosis

65
Q

what is seen on histology in someone with ewings sarcoma

A

small round cells with clear cytoplasm on haematoxylin and eosin staining

66
Q

what are the 2 common causes of not passing meconium

A

cystic fibrosis
hirschsprungs disease

67
Q

what rf ellicit OGGT in pregnancy?

A

BMI >30
previous macrosomic baby
previous gestational diabetes
1st degree relative with diabetes
ethnic origin

68
Q

when is OGTT in pregnancy done?

A

26-28 weeks

69
Q

what folic acid supplementation is recommended for pregnant women? include doses and times

A

400 mcg folic acid daily until 12th week

70
Q

what is the high dose for folic acid supplementation in pregnant women?

A

5mg

71
Q

what is seen in the baby when there is maternal alcohol consumption

A

congential heart defects (VSDs)
abnormal face: thin lips, smooth philtrum, small jaw

72
Q

how uterine atony addressed in PPH?

A

IV oxytocin
Bimanual uterine compression

73
Q

what is erbs palsy, whats it associated with and how is it managed?

A

palsy of the arm: flaccid upper arm, extended lower arm rotated towards body and hand in waiters tip position
associated with shoulder dystocia- damage to brachial plexus
usually resolves in 12 months

74
Q

what bloods would you do in someone with alcohol withdrawal?

A

TFTs
FBC
ESR
CRP
B12
folate
UEs
LFTs
BG and Hba1c

75
Q

what is first line treatment for acute mania?

A

antipsychotics
(those with mood stabilising properties are used and include olanzipine, haloperidol, risperidone, quetiapine)

76
Q

what electrolyte abnormality may be seen in someone after a panic attack? why?

A

hypocalcaemia
hyperventilation causes alkalosis with promotes calcium binding to albumin

77
Q

how does osteosarcoma in a child usually present?

A

localised pain for several months not associated with trauma or injury, sometimes palpable lump

78
Q

whats the most common primary malignant bone tumor in kids and adolescents?

A

osteosarcoma

79
Q

what depth are compressions done in paediatric basic life support?

A

1/3rd chest depth

80
Q

how do you differentiate transient synovitis and septic arthritis?

A

joint aspirate- septic arthritis will grow bacteria and transient synovitis wont

81
Q

how does tetralogy of fallot present?

A

tet spells- episodic syanosis
left lower sternal edge murmur

82
Q

how does transposition of the great arteries present?

A

constant cyanosis
appears hours after birth
prominent right venticular heave
single second heart sound

83
Q

where does fluid accumulate in a hydrocele?

A

tunica vaginalis

84
Q

when is surgery for a hydrocele required?

A

if persistent beyond the age of 2

85
Q

how long is folic acid taken for?

A

before conception through to 12 weeks

86
Q

what are indications for high dose folic acid?

A

partner with NTD
previous pregnancy with NTD
coeliac disease
diabetes
thalassaemia trait
obese

87
Q

what microbio tests are done at booking appt?

A

HIV
Hep B
spyhillis

88
Q

how long should you take iron for if you are anemic?

A

3 months
even if levels are normal

89
Q

what do you need to screen for when someone presents with suspected pre eclampsia

A

HELPP syndrome

90
Q

how is hyperemesis gravidarum managed?

A

electrolyte and fluid replacement
anti histamine first line (cyclizine or prochlorperazine) then anti emetics (ondansetron/metacloperamide)
thiamine and folic acid supplementation to prevent wernickes enceph
TED stockings to reduce risk of thrombosis due to pregnancy, dehydration and immobilisation

91
Q

how is primary ovarian insufficiency diagnosed?

A

menopausal sx
2 elevated FSH 4-6 weeks apart

92
Q

when is the booking appt done?

A

8-10 weeks

93
Q

what cancers does PCOS increase the risk of?

A

endometrial and ovarian

94
Q

when are anti D rhesus injections given?

A

one injection 28-30 weeks
2 injections one at 28 weeks and one at 34 weeks

95
Q
A