Visual Failure Flashcards

1
Q

The commonest cause of visual dysfunction is a

________

A

simple refractive error.

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2
Q

The WHO defines blindness as ‘best visual acuity less than ______

A

3/60’,

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3
Q

in Australia eligibility for the blind pension is ‘bilateral corrected visual acuity less than _________ or significant visual field loss’ (e.g. a patient can have 6/6 vision but severely restricted fields caused by chronic open-angle glaucoma).

A

6/60

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4
Q

The commonest causes of sudden visual loss are

____ and ________

A

transient occlusion of the retinal artery (amaurosis

fugax) and migraine

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5
Q

‘Flashing lights’ are caused by traction on the
retina and may have a serious connotation: the
commonest cause is________

A

vitreoretinal traction, which is

a classic cause of retinal detachment.

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6
Q

The presence of floaters or ‘blobs’ in the visual
fields indicates pigment in the vitreous: causes
include _______ and _____

A

vitreous haemorrhage and vitreous detachment

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7
Q

______is the commonest
cause of the acute onset of floaters, especially with
advancing age

A

Posterior vitreous detachment

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8
Q

Retinal detachment has a tendency to occur in

________

A

short-sighted (myopic) people

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9
Q

Suspect a _________ where objects look

smaller or straight lines are bent or distorted.

A

macular abnormality

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10
Q

Central visual loss presents as
impairment of visual acuity and implies defective
_____ or __________

A

retinal image formation (through refractive error or
opacity in the ocular media) or macular or optic nerve
dysfunction

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11
Q

It is important to differentiate the central field

loss of macular degeneration from the _________

A

hemianopia of a CVA.

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12
Q

2 drugs which are oculotoxic

A

ethambutol and quinine/chloroquine

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13
Q

Questions specific Sx

Presence of floaters → normal ageing (especially
≥ 55 years) with posterior vitreous detachment
or may indicate _____ or ______

A

haemorrhages or choroiditis

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14
Q

Questions specific Sx

Flashing lights → normal ageing with posterior
vitreous detachment or indicates _______

A

traction on the

retinal

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15
Q

Questions specific Sx

Coloured haloes around lights → ____ and _____

A

glaucoma and cataract

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16
Q

Questions specific Sx

Zigzag lines → _________

A

migraine

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17
Q

Questions specific Sx

Vision worse at night or in dim light →

A

retinitis

pigmentosa, hysteria, syphilitic retinitis

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18
Q

Questions specific Sx

Headache → _____

A

temporal arteritis, migraine, benign intracranial hypertension

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19
Q

Questions specific Sx

_________ → macular disease, optic
neuritis

A

Central scotomata

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20
Q

Pain on moving eye → _________

A

retrobulbar neuritis

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21
Q

Distortion, micropsia (smaller), macropsia

(larger) → _________

A

macular degeneration

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22
Q

Visual field loss:

— central loss—_________
— total loss—______
— peripheral loss

A

macular disorder

arterial occlusion

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23
Q

It is worth noting that if a patient repeatedly
knocks into people and objects on a particular
side (including traffic accidents), a _________

A

bitemporal or homonymous hemianopia should be suspected

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24
Q

Almost half the causes of blindness are genetically determined, in contrast to the ____ and _______causes that predominate in third world countries.

A

nutritional and infective

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25
Q

About ________ of children will fail to develop proper vision in at least one eye.

A

3%

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26
Q

The eyes of all babies should be examined at birth

and at ________

A

6 weeks

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27
Q

______ is defined as a reduction in visual acuity due

to abnormal visual experience in early childhood.

A

Amblyopia

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28
Q

What is the cause of amblyopia

A

caused by interference with visual

development during the early months and years of life.

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29
Q

Common causes of amblyopia

A
  • strabismus
  • large refractive defect, especially hypermetropia
  • congenital cataract
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30
Q

The two serious squints are the ______and
______ones, which require early referral.
Transient squint and latent squint (occurs under
stress e.g. fatigue) usually are not a problem

A

constant

alternating

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31
Q

Always refer children with strabismus (squint)

when first seen to exclude ocular pathology such as

A

retinoblastoma, congenital cataract and glaucoma,

which would require emergency surgery

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32
Q

The younger
the child, the easier it is to treat amblyopia; it may
be irreversible if first detected later than _____

A

school

age

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33
Q

Problems with cataracts in children

A

development of vision may be permanently impaired

amblyopia

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34
Q

Cataracts are diagnosed by looking at
the _______and this should be a routine part of the
examination of a young child

A

red reflex

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35
Q

Common conditions
causing cataracts are ____ and _____
but most causes are unknown.

A

genetic disorders and rubella

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36
Q

Refractive errors, with the error greater in one eye,

can cause _______

A

amblyopia

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37
Q

_______, although rare, is the commonest
intraocular tumour in childhood. It must be excluded
in any child presenting with a white pupil

A

Retinoblastoma

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38
Q

What reflex do RB patients have?

A

Such children also have the so-called ‘cat’s eye reflex’.

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39
Q

_______ in its various forms is
the commonest cause of visual deterioration in the
elderly

A

Macular degeneration

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40
Q

Most patients with a vision of ______
or worse in both eyes usually benefit from cataract
extraction, but some can cope with this level of vision
and rely on a good, well-placed (above and behind)
reading light

A

6/18

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41
Q

Sudden loss of vision in the elderly is suggestive
of__ and _______so this
problem should be checked

A

temporal arteritis or vascular embolism,

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42
Q

Pathophysio of devt of floaters

A

When the vitreous gel shrinks as part of the normal
ageing process, it tugs on the retina (rods and cones),
causing flashing lights. When the gel separates from
the retina, floaters (which may appear as dots, spots
or cobwebs) are seen

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43
Q

FLoates can also be soon in whom?

A

myopic or who have had eye surgery such

as removal of cataracts

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44
Q

In the normal eye (emmetropia) light rays from
infinity are brought to a focus on the retina by the
_______ (contributing about two-thirds of the eye’s
refractive power) and the ______(one-third).

A

cornea

lens

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45
Q

the cornea is very important in refraction and
abnormalities such as _____ may cause severe
refractive problems

A

keratoconus

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46
Q

The process of ________ is required for
focusing closer objects. This process, which relies on the
action of ciliary muscles and lens elasticity, is usually
affected by ageing,

A

accommodation

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47
Q

Highly myopic eyes may develop____ or _____

A

retinal detachment or macular degeneration.

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48
Q

Mx of Myopia

A

• Glasses with a concave lens
• Contact lenses
• Consider radial keratotomy or excimer laser
surgery

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49
Q

This condition is more susceptible to closed angle

glaucoma.

A

Hypermetropia (long-sightedness)

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50
Q

Hypermetropia (long-sightedness) is asstd with what condition in early childhood?

A

In early childhood it may be associated

with convergent strabismus (squint).

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51
Q

There is a need for near correction with loss of

accommodative power of the eye in the 40s. What condition?

A

Presbyopia

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52
Q

This creates the need for a corrective lens that is more
curved in one meridian than another because the
cornea does not have even curvature

A

Astigmatism

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53
Q

Cx of astigmatism

A

If uncorrected,

this may cause headaches of ocular origin

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54
Q

_______ is one cause of astigmatism.

A

Conical

cornea

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55
Q

If visual acuity is not
normalised by looking through a card with a 1 mm
pinhole, then the defective vision is not solely due to
a _______

A

refractive error.

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56
Q

The term ‘cataract’ describes any_________

A

lens opacity

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57
Q

Cataract causes gradual visual loss with

normal direct___________

A

pupillary light reflex

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58
Q

Causes of progressive B visual loss

From the globe: ________

A

Chronic glaucoma

Senile cataracts

59
Q

Causes of progressive B visual loss

From the Retina: ________

A
Macular degeneration
Retinal disease:
• diabetic retinopathy
• retinitis pigmentosa
• choroidoretinitis
60
Q

Causes of progressive B visual loss

From the Optic nerve

A

Optic neuropathies
Optic nerve compression (e.g.
aneurysm, glioma)
Toxic damage to optic nerves

61
Q

Causes of progressive B visual loss

From the Optic chiasma

A

Chiasmal compression: pituitary

adenoma, craniopharyngioma, etc.

62
Q

Causes of progressive B visual loss

From the Occipital cortex

A

Tumours

Degenerative conditions

63
Q

The _______ is a reflection of the fundus when the
eye is viewed from a distance of about 60 cm (2 feet)
with the ophthalmoscope using a zero lens.

A

‘red reflex’

64
Q

Contraindications for extraction of cataract include ____ and _____

A

intraocular inflammation and severe diabetic retinopathy

65
Q

The removal of the cataractous lens requires
optical correction to restore vision and this is usually
performed with an __________

A

intraocular lens implant

66
Q

For cataract, Complications are uncommon yet many patients may require _______ to clear any opacities that may develop behind the lens implant

A

YAG laser capsulotomy

67
Q

What drugs can be given to post op cataract

A

— steroids (to reduce inflammation)
— antibiotics (to avoid infection)
— dilators (to prevent adhesions

68
Q

Sunglasses, particularly those that wrap around and

filter UV light, may offer protection against ______

A

cataract

formation

69
Q

_______ is the commonest cause of

irreversible blindness in middle age

A

Chronic simple glaucoma

70
Q

Features of chronic glaucoma

A
  • Familial tendency
  • No early signs or symptoms
  • Central vision usually normal
  • Progressive restriction of visual field
71
Q

Findings in glaucoma

Tonometry
• Upper limit of normal is_______ mmHg

Ophthalmoscopy
• Optic disc cupping ______ of total disc area

A

22

> 30%

72
Q

Meds for glaucoma used for life

A

— timolol or betaxolol drops bd

73
Q

What other drugs can be given for pts with glaucoma

A

— latanoprost drops, once daily
— pilocarpine drops qid
— dipivefrine drops bd
— acetazolamide (oral diuretics)

74
Q

Primary degeneration of the retina is a hereditary
condition characterised by a degeneration of rods
and cones associated with displacement of melanincontaining cells from the pigment epithelium into the more superficial parts of the retina

A

Retinitis pigmentosa

75
Q

Features of RP

  • Begins as ______ in childhood
  • Visual fields become_____
  • Blind by _______
A

night blindness

concentrically narrowed (periphery to centre)

adolescence (sometimes up to middle age

76
Q

What may delay progression of RP

A

Irreversible course—may be delayed by vitamin A

77
Q

Ophtha findings of RP

A

• Irregular patches of dark pigment, especially at
periphery
• Optic atrophy

78
Q

Pain and redness may be minimal with this chronic
inflammation. If untreated, visual loss often develops
from secondary glaucoma and cataract.

A

Chronic uveitis

79
Q

ocular problem with chronic uveitis>

A

The pupil is bound to the lens by synechiae and is distorted

80
Q
AIDS may have serious ocular complications,
including
1
2
3
A

Kaposi sarcoma of the conjunctivae, retinal haemorrhage and vasculitis

81
Q

Problem with HIVs

Another problem is ocular________, which presents as areas of opacification with haemorrhage
and exudates.

A

cytomegalovirus infection

82
Q

_______ is transient loss of vision (partial or
complete) in one eye due to transient occlusion of a
retinal artery. It is painless and lasts less than 60 minutes

A

Amaurosis fugax

83
Q

Amaurosis usually caused by an ______

A

embolus from an atheromatous carotid artery in the neck

84
Q

In Aamurosis, The most common emboli are
______, which usually arise from an ulcerated
plaque

A

cholesterol emboli

85
Q

Unilateral loss of vision provoked by activities such as
walking, bending or looking upwards is suggestive of
______

A

ocular ischaemia

86
Q

What triggers ocular ischaemia?

A

It occurs in the presence of severe
extracranial vascular disease and may be triggered
by postural hypotension and stealing blood from the
retinal circulation.

87
Q

What factors may cause RD

A

Retinal detachment may be caused by trauma, thin
retina (myopic people), previous surgery (e.g. cataract
operation), choroidal tumours, vitreous degeneration
or diabetic retinopathy

88
Q

Classic eye sx of RD

A

‘A curtain came down over the eye’, grey cloud or

black spot

89
Q

In RD, small holes are usually tx by?

A

Small holes treated with laser or freezing probe

90
Q

What may cause vitreous hemorrhage

A

spontaneous rupture of vessels, avulsion of vessels during retinal traction or bleeding from abnormal new vessels

91
Q

Associations of vitreous hemorrhage

A

Associations include ocular trauma, diabetic retinopathy, tumour and retinal detachment.

92
Q

SSx of Vitreous hemorrhage

A
  • Sudden onset of floaters or ‘blobs’ in vision

* May be sudden loss of vision

93
Q

Ophthalmoscopy findings of Vitreous hemorrhage

A

Ophthalmoscopy may show reduced light reflex:
there may be clots of blood that move with the
vitreous (a black swirling cloud

94
Q

Cause of CRAO

A

The cause is usually arterial obstruction by

atherosclerosis, thrombi or emboli

95
Q

SSx of CRAO

A

• Sudden loss of vision like a ‘curtain descending’
in one eye
• Vision not improved with 1 mm pinhole
• Usually no light perception

96
Q

Ophthalmoscopy findings of CRAO

A
  • Initially normal
  • May see retinal emboli
  • Classic ‘red cherry spot’ at macula
97
Q

Mx of CRAO within 30 mins:

massage globe digitally through closed eyelids
(use rhythmic direct digital pressure)—may
______

• rebreathe carbon dioxide (paper bag) or inhale
_______

A

dislodge embolus

special CO 2 mixture (carbogen)

98
Q

Prognosis of CRAO

A

Prognosis is poor. Significant recovery is unlikely

unless treated immediately (within 30 minutes).

99
Q

Factors which may lead to thrombosis

A

Thrombosis is associated with several possible
factors, such as hypertension, diabetes, anaemia,
glaucoma and hyperlipidaemia. It usually occurs in
elderly patients.

100
Q

SSx of Central retinal vein thrombosis

A

• Sudden loss of central vision in one eye (if macula
involved): can be gradual over days
• Vision not improved with 1 mm pinhole

101
Q

Opthalmoscopy findings of Central retinal vein thrombosis

A

Ophthalmoscopy shows swollen disc and multiple

retinal haemorrhages, ‘stormy sunset’ appearance

102
Q

T or F,

In Central retinal vein thrombosis

No immediate treatment is effective

A

No immediate treatment is effective

103
Q

In Central retinal vein thrombosis

_________may be necessary in later stages if
neovascularisation develops to prevent thrombotic
glaucoma.

A

Laser photocoagulation

104
Q

2 types of macular degeneration:

1

2

A

There are two types: exudative or ‘wet’ (acute), and

pigmentary or ‘dry’ (slow onset).

105
Q

________is caused by choroidal neovascular
membranes that develop under the retina of
the macular area and leak fluid or bleed. It is a
serious disorder

A

‘Wet’ MD

106
Q

‘Dry’ MD (9 out of 10 cases of MD) develops

________ and usually ______

A

slowly and is always painless

107
Q

Ssx of MD

A
  • Sudden fading of central vision (see FIG 77.6 )
  • Distortion of vision
  • Straight lines may seem wavy and objects distorted
108
Q

Visual fields of pts with MD

A
  • Central vision eventually completely lost

* Peripheral fields normal

109
Q

What can be seen in the Amsler grid in pts with MD

A

Use a grid pattern (Amsler chart): shows

distorted lines

110
Q

Ophtalmoscopy findings of MD

A
  • White exudates, haemorrhage in retina

* Macula may look normal or raised

111
Q

What is the Tx for wet MD

A

For ‘wet’ MD refer urgently for treatment, which
is currently based on injection of antivascular
endothelial growth factor drugs (ranibizumab
or bevacizumab) into the vitreous humour

112
Q

What is the Tx for dry MD

A

No treatment is available to stop or reverse MD

113
Q

Age-Related Eye Disease Study provided confirmatory
evidence that the chronic pigmentation
type responds to free-radical treatment with the

A

antioxidants vitamins A, C, E, and zinc using betacarotene,
15 mg; vitamin C, 500 mg; vitamin E,
400 IU; and 80 mg zinc oxide

114
Q

With _____________there is
a risk of sudden and often bilateral occlusion of the
short ciliary arteries supplying the optic nerves, with
or without central retinal artery involvement.

A

temporal arteritis (giant cell arteritis)

115
Q

What vision is lost in pts with temporal arteritis

A

Sudden loss of central vision in one eye (central

scotoma)

116
Q

Neuro PE of pts with temporal arteritis

A

Afferent pupil defect on affected side

117
Q

Labs of pts with temporal arteritis

A

Usually elevated ESR >40 mm

118
Q

Ophthalmoscopy findigs of temporal arteritis

A

Ophthalmoscopy shows optic disc swollen at first,

then atrophic. The disc may appear quite normal

119
Q

Tx for temporal arteritis

A

• Immediate corticosteroids (60–100 mg

prednisolone daily for at least 1 week

120
Q

In pts with temporal arteritis

What to do if there is a localised tender area)

A

Biopsy temporal artery

121
Q

Migraine may present with symptoms of visual loss.

Associated headache and nausea may not be present

A

Retinal migraine

122
Q

SSx of retinal migraine

A
  • Zigzag lines or lights

* Multicoloured flashing lights

123
Q

What condition

The vitreous body collapses and detaches from the
retina. It may lead to retinal detachment

A

Posterior vitreous detachment

124
Q

Ssx of Posterior vitreous detachment

A
  • Sudden onset of floaters
  • Visual acuity usually normal
  • Flashing lights indicate traction on the retina
125
Q

Causes of Optic (retrobulbar) neuritis

A

Causes include multiple sclerosis, neurosyphilis and

toxins

126
Q

What vision is lost in Optic (retrobulbar) neuritis

A
  • Usually a central field loss (central scotoma)

* Afferent pupil defect on affected side

127
Q

Ophtha findings of Optic (retrobulbar) neuritis

A

• Optic disc swollen if ‘inflammation’ anterior in
nerve
• Optic atrophy appears later
• Disc pallor is an invariable sequel

128
Q

Patients with ________ typically suffer from

ocular pain or discomfort and reduced vision

A

corneal conditions

129
Q
Inflammation of the cornea—keratitis—is
caused by factors such as 
1
2
3
4
A

ultraviolet light e.g. ‘arc eye’, herpes simplex, herpes zoster ophthalmicus and the dangerous ‘microbial keratitis

130
Q

______ is an ophthalmological emergency that should be
considered in the contact lens wearer presenting
with pain and reduced vision.

A

Bacterial keratitis

131
Q

Pittfalls

• Mistaking the coloured haloes of________for
migraine.
• Failing to appreciate the presence of retinal
detachment in the presence of______

A

glaucoma

minimal visual
impairment

132
Q

Pittfalls

• Omitting to consider ______as a cause
of sudden visual failure in the elderly.

• Using eyedrops to dilate the pupil (for fundal
examination) in the presence of _______

A

temporal arteritis

glaucoma

133
Q

Tonometry is advised routinely for all people over
______ years; those over 60 years should have tests
every 2 years

A

40

134
Q

T or F

Any family history of glaucoma requires tonometry
at earliest age

A

T

135
Q

Temporal arteritis is an important cause of _____

A

retinal artery occlusion

136
Q

Suspect field defect due to ________ if

people are misjudging when driving.

A

chiasmal compression

137
Q

Central retinal artery occlusion may be overcome

by ________

A

early rapid lowering of intraocular pressure

138
Q

Keep in mind antioxidant therapy (vitamins and

minerals) for________

A

chronic macular degeneration

139
Q

Consider _________ foremost if there is a
past history of transient visual failure, especially
with eye pain

A

multiple sclerosis

140
Q

Considerations for the ff time scales

Sudden: less than 1 hour

A
Amaurosis fugax
Central retinal artery occlusion
Hemianopias from ischaemia (emboli)
Migraine
Vitreous haemorrhage
Acute angle glaucoma
Papilloedema
141
Q

Considerations for the ff time scales

Within 24 hours
1
2

A

Central retinal vein occlusion

Hysteria

142
Q

Considerations for the ff time scales

Less than 7 days

A

Retinal detachment
Optic neuritis
Acute macular problems

143
Q

Considerations for the ff time scales

Up to several weeks (variable)

A

Choroiditis

Malignant hypertension

144
Q

Considerations for the ff time scales

Gradual

A
Compression of visual pathways
Chronic glaucoma
Cataracts
Diabetic maculopathy
Retinitis pigmentosa
Macular degeneration
Refractive errors