Viruses and disease

Question 1

what are the steps of viral replication

Answer 1

attachment
entry
uncoating
nucleic acid and protein synthesis
assembly
release

Question 2

attachment

Answer 2

interactions with specific receptors in target cell

Question 3

entry

Answer 3

by endocytosis

Question 4

uncoating

Answer 4

viral nucleic acid released from capsid

Question 5

nucleic acid and protein synthesis

Answer 5

host ribosome used
host polymerases may be used

Question 6

assembly

Answer 6

nucleic acid and proteins packaged together

Question 7

what are two ways release can occur ?

Answer 7

budding
lysis

Question 8

budding

Answer 8

virus released with envelope derived from host cell membrane
doesnt kill cell

Question 9

lysis

Answer 9

virus accumulate until bursts
kills cell

Question 10

what release kills cell ?

Answer 10

lysis

Question 11

how are virus detected ?

Answer 11

PCR
antigen detection

Question 12

how can immunity develop from virus infection ?

Answer 12

cytotoxic T lymphocytes
neutralising antibodies

Question 13

how do cytotoxin T lymphocytes work ?

Answer 13

recognise proteins on cell surface as being foreign
signals infected cell to commit suicide in order to prevent formation of new viruses

Question 14

what are the neutralising antibodies ?

Answer 14

IgG
IgM

Question 15

what do neutralising antibodies prevent ?

Answer 15

prevent virus binding to cellular receptors