antigens Flashcards
what immune response do antigens cause ?
cause an adaptive immune response
what cells do antigens activate
B and T cells
how do T cells have that recognise pathogen ?
has alpha and beta chain
what does T cell antigen receptor contain ?
membrane-bound protein heterodimer
what does B cell antigen receptor contain ?
membrane bound antibody (IgM or IgD)
what does B cell antigen receptors have that help recognise pathogen ?
light and heavy chain and disulphide bridges
how are pathogens found ?
secondary lymphoid tissues
what are the steps antigens undertake ?
find the pathogen
activate
respond
what can be activated ?
MHC/HLA porteins
class 1
class 2
what do MHC/HLA do ?
display peptide antigens to T cells
what cells do class 1 work on ?
expressed on all nucleated cells
what do class 1 do ?
present peptide antigens to cytotoxic T cells
what cells do class 2 work on ?
expressed on:
dendritic cells
macrophages
B cells
what do class 2 do ?
present peptide antigens to helper T cells
