acute inflammation Flashcards
what is apoptosis ?
programmed cell death
what does apoptosis defend against ?
defence inherited and injury
what is response to injury ?
vascular changes
cellular changes
chemical mediators
morpholigical patterns
what is vascular changes ?
dilation and increased permeability of blood vessels
what are cellular changes ?
stasis (slowing down)
white cell margination
rolling
adhesions
migration
what occurs in the cellular phase ?
fluid and cells escape from permeable venules
what are beneficial effects of acute inflammation ?
Toxin dilution
Entry of antibodies
Fibrin formation
Drug transport
Oxygen and nutrient delivery
Immune response stimulation
what are harmful effects of acute inflammation ?
Digestion of normal tissues
Swelling
Inappropriate inflammatory response – type 1 hypersensitivity
what is chronic inflammation ?
prolonged tissue reactions that follow initial reaction
what leads to chronic inflammation ?
recurrence of acute inflammation
what are characteristics of inflation
Redness – due to dilatation of small blood vessels
Heat – increased blood flow through region
Swelling – accumulation of fluid in extravascular space
Pain – distortion of tissues
Loss of function – inhibited by pain or swelling