Virulence factors Flashcards

1
Q

Refers to the ability of an organism to cause a disease

A. Pathogenicity
B. Virulence
C. Virulence factor

A

A. Pathogenicity

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2
Q

Refers to the degree of pathology caused by the organism

A. Pathogenicity
B. Virulence
C. Virulence factor

A

B. Virulence

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3
Q

Structure, toxin, adhesion, etc that contributes to the ability of a pathogen to cause a disease

A. Pathogenicity
B. Virulence
C. Virulence factor

A

C. Virulence factor

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4
Q

Pili aka fimbriae can serve as _____ factors to allow attachment to cells

A

adherence

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5
Q

What kind of pili is involved in gene transfer?

A

Sex pili

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6
Q

What are the two genera of bacteria that can form endospores?

A
  1. Baccillus

2. Clostridium

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7
Q

Bacteria that are phagocytized by macrophages and still survive by inhibiting phagosome-lysosome fusion are called _____________ organisms

A

Facultative intracellular organisms

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8
Q

Part of the outer membrane

Endotoxin or exotoxin

A

Endotoxin

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9
Q

Part of the LPS (lipid A) of G- bacteria

Endotoxin or exotoxin

A

Endotoxin

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10
Q

Treating pt with a G- infections w/ antibiotics can worsen the disease

Endotoxin or exotoxin

A

Endotoxin

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11
Q

Shed in steady amounts by living bacteria

Endotoxin or exotoxin

A

Endotoxin

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12
Q

Can act outside of host, on cell membrane or inside cells

Endotoxin or exotoxin

A

Exotoxin

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13
Q

What is bacteremia?

A

Bacteria in blood

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14
Q

What is sepsis?

A

Bacteremia that causes systemic immune response to infection

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15
Q

What is often the stimulus of septic shock?

A

Endotoxin (LPS)

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16
Q

What causes septic shock?

A

G- and G+ bacteria

17
Q

What happens to your body during septic shock?

A

Drop in BP + multi-organ failure

18
Q

What is the major mediator in septic shock?

A

Tumor necrosis factor (TNF)