virology - pathogenesis, prevention and therapy,

Question 1

3 viral clinical presentation of virus

Answer 1

acute
latent
chronic or persistent

Question 2

this clinical presentation of virus displays all the evident signs and symptoms

Answer 2

acute viral infection

Question 2

this clinical presentation of virus show no signs and symptoms, but the virus is still present in the host cell in lysogenic state or maintained as a nuclear or cytoplasmic episome

Answer 2

latent infection

Question 3

lysogenic state means

Answer 3

inserted into the host genome in a resting state

Question 4

this clinical presentation of virus in which low levels of virus are detectable and the degree of visible signs or symptoms varies

Answer 4

chronic or persistent infection

Question 5

an infection after local or mucosal site where it disseminated in peripheral blood is called as

Answer 5

viremia

Question 6

it results due to lysis of virus infected cells or by immunopathologic mechanisms directed against the virus that are also destructive to neighboring tissue

Answer 6

tissue damage

Question 7

occasionally, pathogenic viruses stimulate an immune reaction that cross reacts with antigenically similar components of the host tissue, resulting in impairment to host function, this phenomenon is called as

Answer 7

autoimmune pathogenesis

Question 8

viruses with the ability to stimulate uncontrolled growth of host cells are referred to as

Answer 8

oncogenic viruses

Question 9

example of oncogenic viruses (oncoviruses )

Answer 9

Human papillomaviruses

Question 10

cross reaction caused by measle infection to CNS results in

Answer 10

SSPE - subacute sclerosing panencephalitis

Question 11

for viruses with no available vaccine, the most effective means of preventing infection involves ___

Answer 11

regular, thorough hand washing and avoiding contact with other during episodes of evident signs of disease such as fever, cough, diarrhea, and respiratory distress

Question 12

how many licensed antiviral drugs for clinical use and approved in US?

Answer 12

more than 70

Question 13

the combination treatment using antiviral drugs are termed as

Answer 13

antiretroviral therapy (ART ) of HIV infections

Question 14

give viruses in which we are using antiviral drugs

Answer 14

hepatitis C virus (HCV)
herpes viruses (HSV)
varicella-zoster (VZV)
cytomegalovirus (CMV)
hepatitis B virus (HBV)
respiratory syncytial virus (RSV)
influenza virus