VIRO: FE RHABDO-BORNA

Question 1

What is the shape of Rhabdoviridae in vertebrates?

Answer 1

Bullet- or conical-shaped

Question 2

It is the site of Rhabdoviridae replication.

Answer 2

Cytoplasm

Question 3

The viral genus that includes the Rabies virus.

Answer 3

Lyssavirus

Question 4

This virus causes Vesicular Stomatitis in cattle, pigs, and horses.

Answer 4

Vesiculovirus

Question 5

What is another name for Bovine Ephemeral Fever?

Answer 5

3-day stiff sickness

Question 6

The primary diagnostic test for Rabies in animal brains.

Answer 6

Direct fluorescent antibody test

Question 7

These are the three phases of Rabies infection.

Answer 7

Prodromal, furious (excitative), and dumb (paralytic)

Question 8

What is the primary reservoir for urban rabies?

Answer 8

Dogs

Question 9

This test detects Negri bodies in Rabies diagnosis.

Answer 9

Histopathology

Question 10

What is the primary mode of transmission for Bovine Ephemeral Fever?

Answer 10

Arthropod vectors

Question 11

This viral genus causes hemorrhagic fever in primates.

Answer 11

Filoviridae

Question 12

The main vector suspected in transmitting Bovine Ephemeral Fever.

Answer 12

Culicine and anopheline mosquitoes

Question 13

It is the most common diagnostic method for Vesicular Stomatitis.

Answer 13

RT-PCR

Question 14

What zoonotic virus resembles influenza in humans?

Answer 14

Vesicular Stomatitis Virus

Question 15

The highly lethal viruses causing severe hemorrhagic fever.

Answer 15

Ebola and Marburg viruses

Question 16

This viral family has long, filamentous, pleomorphic forms.

Answer 16

Filoviridae

Question 17

What is the incubation period of Marburg and Ebola viruses?

Answer 17

4-10 days

Question 18

These viruses are associated with bush meat consumption.

Answer 18

Filoviruses (Ebola and Marburg)

Question 19

The primary cells infected by Bornaviridae.

Answer 19

Neurons and glial cells

Question 20

It is a distinctive inclusion body found in Borna disease virus infection.

Answer 20

Joest-Degen bodies

Question 21

The main route of transmission for Borna Disease Virus.

Answer 21

Oronasal (proposed)

Question 22

This viral family causes Proventricular Dilation Disease in birds.

Answer 22

Bornaviridae

Question 23

What are the main clinical signs of Avian Bornavirus infection?

Answer 23

Neurological and gastrointestinal dysfunction

Question 24

This test detects phosphoprotein (P) in Avian Bornavirus infections.

Answer 24

Immunohistochemistry

Question 25

What is the genetic material of Rhabdoviridae?

Answer 25

Single-stranded negative-sense RNA

Question 26

The primary mode of transmission for Rabies virus.

Answer 26

Bite from an infected animal

Question 27

What inclusion bodies are found in neurons of rabies-infected animals?

Answer 27

Negri bodies

Question 28

It is the gold standard diagnostic test for Rabies.

Answer 28

Direct fluorescent antibody test (dFA)

Question 29

The vaccine used to prevent Rabies in humans and animals.

Answer 29

Inactivated (killed) rabies vaccine

Question 30

What is the post-exposure prophylaxis for Rabies?

Answer 30

Rabies vaccine and rabies immunoglobulin

Question 31

The primary host species for Lyssaviruses.

Answer 31

Mammals

Question 32

Which organ is the main target of Bovine Ephemeral Fever?

Answer 32

Skeletal muscles and joints

Question 33

It is the causative agent of African Horse Sickness.

Answer 33

Orbivirus

Question 34

The primary route of transmission for Filoviruses.

Answer 34

Direct contact with infected body fluids

Question 35

This virus is responsible for the deadliest hemorrhagic fever outbreaks.

Answer 35

Ebola virus

Question 36

The major symptoms of Filovirus infection.

Answer 36

Severe hemorrhagic fever, organ failure, shock

Question 37

What is the causative agent of Marburg Hemorrhagic Fever?

Answer 37

Marburg virus

Question 38

The method used for rapid detection of Filoviruses.

Answer 38

RT-PCR (Reverse Transcription Polymerase Chain Reaction)

Question 39

This Filovirus species caused the largest Ebola outbreak in history.

Answer 39

Zaire ebolavirus

Question 40

What virus is responsible for Borna disease?

Answer 40

Borna Disease Virus (BDV)

Question 41

The main neurological sign of Borna Disease in horses.

Answer 41

Behavioral changes and ataxia

Question 42

What type of immune response is linked to Borna Disease Virus pathology?

Answer 42

T-cell mediated immune response

Question 43

This term describes the prolonged viral persistence in Bornavirus infections.

Answer 43

Latency

Question 44

Which diagnostic method detects Bornavirus RNA?

Answer 44

RT-PCR

Question 45

What are the main hosts of Avian Bornavirus?

Answer 45

Parrots and psittacine birds

Question 46

What disease is caused by Avian Bornavirus?

Answer 46

Proventricular Dilatation Disease (PDD)

Question 47

This histopathological feature is characteristic of Avian Bornavirus infection.

Answer 47

Lymphoplasmacytic ganglioneuritis