VIRO: FE RETRO-PNEUMO Flashcards

1
Q

What enzyme transcribes viral RNA into double-stranded DNA in Retroviridae?

A

Reverse transcriptase

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2
Q

It is the enzyme responsible for integrating viral DNA into the host genome.

A

Integrase

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3
Q

The term ‘Retro’ in Retroviridae refers to what process?

A

Reverse transcription

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4
Q

These retroviruses are capable of horizontal transmission.

A

Exogenous retroviruses

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5
Q

These retroviruses are remnants of ancient infections integrated into host DNA.

A

Endogenous retroviruses

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6
Q

What does the gag gene encode?

A

Major structural nonglycosylated polyproteins

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7
Q

The pol gene in retroviruses encodes what proteins?

A

Reverse transcriptase and integrase enzyme

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8
Q

It is the genus of retroviruses that induce neoplastic transformation in cells.

A

Oncogenic retroviruses

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9
Q

This retrovirus genus causes lifelong infections with long incubation periods.

A

Lentivirus

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10
Q

What is the primary mode of transmission for Feline Immunodeficiency Virus (FIV)?

A

Bites (through saliva)

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11
Q

These are the four clinical phases of FIV infection.

A

Acute, prolonged asymptomatic, vague clinical signs, terminal phase

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12
Q

This test is used for diagnosing Equine Infectious Anemia.

A

AGID test (Coggins test)

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13
Q

The primary cells targeted by Maedi/Visna virus.

A

Monocytes

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14
Q

It is the primary source of Small Ruminant Lentivirus transmission.

A

Milk from infected animals

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15
Q

What are the main genera of Birnaviridae?

A

Avibirnavirus, Aquabirnavirus, Blosnavirus, Entomobirnavirus

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16
Q

What is the common name for Infectious Bursal Disease?

A

Gumboro Disease

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17
Q

The main target cells of Infectious Bursal Disease Virus (IBDV).

A

B lymphocytes in the bursa of Fabricius

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18
Q

The primary route of transmission for IBDV.

A

Oral route

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19
Q

What is the key feature of the nucleocapsid in Paramyxoviridae?

A

Helical symmetry with herring-bone appearance

20
Q

The genus of Paramyxoviridae that causes Newcastle Disease.

A

Avulavirus

21
Q

This strain of Newcastle Disease Virus is the most pathogenic.

22
Q

It is the causative agent of ‘Sheep and Goat Plague’.

A

Peste des Petits Ruminants (PPR)

23
Q

The viral genus responsible for Canine Distemper.

A

Morbillivirus

24
Q

What viral genus includes the pathogen for ‘Blue Eye Disease’ in pigs?

A

Rubulavirus

25
Q

These viruses use G protein for cell attachment instead of hemagglutinin and neuraminidase.

A

Pneumoviridae

26
Q

This virus causes Swollen Head Syndrome in chickens.

A

Avian Metapneumovirus (Type A & B)

27
Q

What is the primary replication site for Paramyxoviridae?

28
Q

These cellular structures are formed due to Paramyxovirus infection.

A

Syncytia and intracytoplasmic inclusions

29
Q

The natural reservoir for Henipaviruses.

A

Pteropus sp. (Fruit bats)

30
Q

This Henipavirus causes severe respiratory disease in horses.

A

Hendra Virus

31
Q

It is the amplifying host for Nipah Virus.

32
Q

What are the three strains of Newcastle Disease Virus?

A

Velogenic, Mesogenic, Lentogenic

33
Q

This genus includes Bovine Parainfluenza Virus 3, associated with ‘shipping fever’.

A

Respirovirus

34
Q

What virus in Paramyxoviridae causes mumps?

A

Rubulavirus

35
Q

This virus in Pneumoviridae is a major cause of respiratory disease in cattle.

A

Bovine Respiratory Syncytial Virus

36
Q

What genus does Turkey Rhinotracheitis virus belong to?

A

Metapneumovirus

37
Q

The primary vector of Equine Infectious Anemia.

A

Haematophagous insects (e.g., Tabanus spp., Stomoxys spp.)

38
Q

This term describes the presence of multiple petechiae in visceral organs of fish with Infectious Pancreatic Necrosis.

A

Ropey mucus

39
Q

What type of genome do Birnaviridae viruses have?

A

Double-stranded RNA (dsRNA)

40
Q

This retrovirus genus is known for causing immunodeficiency diseases in animals.

A

Lentivirus

41
Q

What is the most prominent lesion caused by Infectious Bursal Disease?

A

Cloacal bursa (bursa of Fabricius)

42
Q

This type of retrovirus has a high mutation rate due to errors in reverse transcription.

A

Retroviridae

43
Q

What serological test is commonly used to diagnose Feline Immunodeficiency Virus?

44
Q

This virus is implicated in chronic stomatitis and gingivitis in cats.

A

Feline Immunodeficiency Virus (FIV)

45
Q

The primary cells targeted by Equine Infectious Anemia Virus.

A

Macrophages, monocytes, Kupffer cells

46
Q

This term describes an ancient retroviral infection where viral DNA is integrated into the host genome.

A

Endogenous retrovirus