PATHO LEC: MOD 4 Flashcards
This term defines the vascular and cellular response of living tissue to injury.
Inflammation
The primary identifying feature of inflammation.
Reaction of blood vessels
The process by which lost or destroyed cells are replaced by vital cells.
Repair
This ancient physician described the four cardinal signs of inflammation.
Cornelius Celsus
The fifth cardinal sign of inflammation, added by Galen.
Loss of function
The scientist who discovered phagocytosis and its role in inflammation.
Elie Metchnikoff
The primary goal of the inflammatory response.
Destroy, dilute, or wall off injurious agents
The suffix used to identify inflammation in an organ or tissue.
-itis
The two primary outcomes of the repair process following injury.
Regeneration and scar formation
The duration of acute inflammation.
Few minutes to 1-2 days
The type of leukocyte predominantly involved in acute inflammation.
Neutrophils
The intermediate stage of inflammation between acute and chronic.
Subacute inflammation
This type of inflammation is of longer duration and involves lymphocytes and macrophages.
Chronic inflammation
The scientist who revealed the vascular alterations in inflammation.
Julius Cohnheim
This component of blood dilutes the effects of an irritant in inflammation.
Edematous fluid
This protein acts as a physical barrier to confine an irritant in inflammation.
Fibrin
This process involves neutrophils and macrophages engulfing harmful agents.
Phagocytosis
The term for fluid and cellular debris associated with the inflammatory response.
Exudate
A disease that arises suddenly and progresses rapidly.
Acute disease
A disease that develops slowly and persists for a long time.
Chronic disease
This phase of inflammation includes changes in vascular flow and caliber.
Hemodynamic changes
The immediate response of arterioles following injury.
Transient vasoconstriction
The primary and fundamental event in inflammation involving increased blood flow.
Vasodilation
The process of increased blood flow to an injured area.
Active hyperemia
The phase of inflammation where leukocytes line the endothelial walls.
Pavementing
The active movement of leukocytes out of the blood vessels.
Emigration
The passive movement of red blood cells through the vascular wall.
Diapedesis
The term describing the outward movement of plasma fluid and leukocytes in inflammation.
Exudation
The scientist who studied the chemotactic movement of leukocytes.
Elie Metchnikoff
This term describes the slowing or stoppage of blood flow in inflammation.
Stasis
This inflammatory mediator is released by mast cells and causes vasodilation.
Histamine
The type of immune response that involves antibodies.
Humoral immunity
This immune process involves the direct attack of pathogens by immune cells.
Cellular immunity
The white blood cells responsible for long-term immune response in chronic inflammation.
Lymphocytes and macrophages
The primary function of neutrophils in acute inflammation.
Phagocytosis of bacteria and debris
This type of exudate is rich in fibrin and is seen in severe inflammation.
Fibrinous exudate
This exudate is composed of dead neutrophils and forms pus.
Purulent exudate
The term for inflammation primarily involving lymphocytes.
Lymphocytic inflammation
The scientist who established the importance of chemical mediators in inflammation.
Julius Cohnheim
This term describes the accumulation of blood due to gravity after death.
Hypostatic congestion
The process in which the body’s temperature equilibrates with the environment after death.
Algor mortis
This postmortem event results in gas accumulation in tissues due to bacterial fermentation.
Postmortem emphysema
The phase of inflammation where neutrophils migrate to the site of injury.
Leukocytic exudation
A major chemical mediator of pain in inflammation.
Bradykinin
The name of the process where leukocytes are attracted to a site of injury.
Chemotaxis
This term describes increased permeability of blood vessels leading to swelling.
Vascular permeability changes
The process by which phagocytes engulf and destroy foreign particles.
Phagocytosis
The scientist who identified the role of neutrophils in bacterial destruction.
Elie Metchnikoff
