VIRO: MEpt2 ASFARVIRIDAE & IRIDO Flashcards
Define Asfarv
African Swine Fever and related virus
Describe Asfarviridae
enveloped
dsDNA
Replication site of Asfar
mainly cytoplasm but nucleus is needed (nucleocytoplasmic)
only known DNA arbovirus
ASF
What is the temp where ASF is stable
4-20C
How to destroy ASF
heating, lipid solvents, disinfectants (orthophenylphenol)
Where is ASF endemic
Subsaharan Africa
Clinical signs of ASF
- hemorrhage, fever (40-42C) dyspnea, vomiting, nasal and conjunctival discharge, reddening or cyanosis of ears, snout and body, and bleeding from nose and anus
what is the mortality rate of being infected with ASF
100%
What are the patterns of transmission
Sylvatic cycle and Domestic cycle
Replication of virus occurs in soft ticks
-what are the routes?
- genus of ticks?
Sylvstic cycle
- transovarial and trans-stadial
- Ornithodoros spp.
Pigs being infected through consumption of tissues from acutely
infected domestic pigs or warthogs
Domestic cycle
Ingestion of uncooked meat from infected pigs
Domestic cycle
Domestic cyle transmission could Spread by direct contact with?
Oronasal
Domestic cycle
Indirect contact can occur through?
contaminated transport vehicles, fomites,
footwear
used for genotyping the virus
p72/p73
Diagnosis for ASF virus?
virus isolation, detection of antigen (e.g. immunofluorescence), PCR,
hemadsorption, ELISA, immunodiffusion
T/F There has been a vaccine developed for ASF.
False, still up for further studies
Infect arthropods, fish, amphibians, reptiles
Iridoviridae
Generas of Iridoviridae
Ranavirus, Megalocytivirus, Lymphocystivirus
Potential factor in global decline of amphibian populations
Ranaviruses
Benign and self-limiting disease described in a broad range of freshwater and
marine fish species
Lymphocystiviruses
emerging and significant impact of this genera on the commercial
production of both food and ornamental fish
Megalocytivirus
