Viral exanthemata and childhood diseases Flashcards
What are the most serious complications of measles?
Pneumonia
Encephalitis
Subacute schlerosing pan encephalitis
What are koplick’s spots diagnostic of?
Measles
What is subacute sclerosing panEncephalitis?
A slow virus infection. Caused by measles virus
invasion of brain. Slow, insidious onset years after
infection. Disappeared in cases with mass vaccination
Clinical manifestations of subacute sclerosing panEncephalitis?
Childhood onset of mental and
behavioral regression with myoclonic jerks (involuntary
jerking of the limbs)
Investigations of subacute sclerosing panEncephalitis?
- EEG: Generalized bilateral rhythmic synchronous
bursts of spike-wave or slow wave complexes - Elevated measles antibody titers in serum and CSF
without concomitant evidence of clinical measles
What is the prevention of measles?
– Live attenuated measles vaccine (MMR) 2 doses
– Normal human immunoglobulin
Treatment of measles
Fluid replacement (with diarrhoea and vomiting) -Vitamin A: two doses 24hours apart to prevent blindness
What is the pattern of rash in rubella?
➢Starts in the face, looks like a heat rash, spreads
downwards. Disappears in the same order
What is the vitamin used in treatment of measles?
Vitamin A
What are the complications of parvo B19 virus
Joint involvement (RA like)
Aplastic crisis
Anemia
Infection
Human herpes virus 6/7 (roseola infuntum) pattern of disease
High fever which lasts for 3 – 5 days and when it drops this is
followed by the sudden appearance of a rose pink macular rash
What is Eczema herpeticum
Extensive cutaneous vesicular eruption of
herpes simplex virus infection in a child with
pre-existing skin disease, usually atopic
dermatitis
Treatment of Eczema herpetcium
Acyclovir
M/C cause of Hand, foot & hand syndrome
Cocksackie virus
Causative agent of glandular fever (infectious mononucleosis)
EBV
