Clinical Approach To Liver Diseases

Question 1

What is the cutoff limit for portal HTN

Answer 1

> 10 mmhg

Question 2

What is the time limit of acute liver cell failure?

Answer 2

<26 weeks

Question 3

What is the time limit of chronic liver failure?

Answer 3

> 26 weeks

Question 4

What is the enzyme deficient in Nieman Pick disease

Answer 4

Sphingomyelinase enzyme

Question 5

What is the enzyme deficient in Gaucher disease?

Answer 5

Glucocerebrosidase that breaks down certain lipids (glucocerebroside)

Question 6

What is the cut off value of direct billirubin in direct hyperbillirubinemia?

Answer 6

> 20% of total billirubin if total >5 mg/dl

Or >1 mg/dl if total <5 mg/dl

Question 7

What is Byler Disease

Answer 7

Progressive familial intrahepatic cholestasis

Question 8

What can a patient with hepatomegaly and hypoglycemia suufer from(disease)

Answer 8

Glycogen storage disease: von gierke or Pompe’s disease

Question 9

A child presents with hepatomegaly and neurological symptoms, this might be….

Answer 9

Neiman pick disease or Wilson’s disease

Question 10

Cl. Pic of Wilson’s disease

Answer 10

Copper deposition in liver(hepatomegaly) , brain (neurological symptoms) , eyes (KF rings)

Question 11

DD of hepatosplenomegaly and anemia

Answer 11

Gaucher disease, LEUKEMIA or lymphoma

Question 12

What are the diseases caised by reduced billirubin conjugation in the liver?

Answer 12

Gilbert disease

Criggler Najjar syndrome