Pediatric Hematology Cases

Question 1

Blood film of ITP shows…..

Answer 1

macrothrombocyte (megakaryocyte)

Question 2

Prognosis of ITP

Answer 2

Resolves within 8 weeks

Question 3

Definitive value of Platelets in ITP

Answer 3

platelets < 100
• Newly diagnosed: < 3mo
• Persistent: 3mo-12mo
• Chronic: >12mo

Question 4

Management of ITP

Answer 4

. IVIG: 1g/kg for 1/2 days
. Steroids:prednisolone 1-2mg/kg/day for a maximum
of 14/7 or
higher doses of steroids (4mg/kg/day
Prednisolone for 4 days)
. Anti- D:
. Tranexamic acid: for dental/ surgical procedures

Question 5

What are the drugs used to prevent tumor lysis syndrome in leukemia?

Answer 5

Allopurinol or Rasburicase