Pediatric Allergy In A Nutchel

Question 1

What are the mechanisms of allergic diseases

Answer 1

IgE mediated

Non IgE mediated

Question 2

Compare between IgE and Non IgE mediated allergy

Answer 2

IgE: Quick onset
• Anaphylaxis
• Well 
defined mechanism
• Easy to 
diagnose
• Validated

Non IgE:
Delayed onset
• Mechanism 
 unclear
• Harder to diagnose
• No validated 
test

Question 3

Treatment of allergic rhinitis (ARIA)

Answer 3

Mild intermittent:
Non sedative H1 blocker
Intranasal decongestant

Mod/ severe intermittent. & Mild Mod Severe persistent:
intra nasal steroid+ local cromone + tx of mild intermittent

In all cases avoid allergen