Video11 pb Drug Side Effects. Flashcards
A 34-year-old man in the hospital is being treated for a severe MRSA (Methicillin Resistance Staphylococcus Aureus Osteomyelitis) when he develops a full body cutaneous flushing.
What is causing the flushing?
Red man syndrome caused byVancomycin as a treatment. Also it is caused by Niacin, Adenosine, Dihydropyridine CCBs.
What drugs have a coronary vasospasm as a potential side effect?
Cocaine, amphetamines, methamphetamines (-triptans) and Ergotamine.
What drugs have a dilated cardiomyopathy as a potential side effect?
Doxorubicin and Daunorubicin.
What drugs have a Torsades de pointes as a potential side effect?
Class III potassium channel blockers, Class IA sodium channel blockers, Macrolides, Haloperidol, Chloroquine and Protease inhibitors.
A 44-year-old woman is in the hospital for a deep venous thrombosis of her right lower leg. After a several days of treatment her platelet count drops to 30,000 per microliter.
What drugs have Thrombocytopenia as a potential side effect?
Heparin and Cimetidine (H2 blocker).
What drugs have Agranulocytosis as a potential side effect?
Clozapine, Carbamazepine, Colchicine, PTU, Methimazole and Dapsone.
What drugs have Aplastic anemia as a potential side effect?
Chloramphenicol, Benzene, NSAIDs, Propylthiuracil (PTU) and Methimazole.
What drugs have Gray baby syndrome as a potential side effect?
Chloramphenicol.
What drugs have Hemolysis in G6PD-deficient patients as a potential side effect?
Isoniazid, Sulfonamides, Primaquine, High-dose aspirin, Ibuprofen, Nitrofurantoin, Dapsone, Fava beans and Naphthalene.
What drugs have Thrombosis as a potential side effect?
Oral contraceptive pills (OCP).
A 56-year-old man presents slowly worsening shortness of breath over the past several months. He denies cough, fever or any other ill-like symptom. He has a PMHx (Past Medical History) of atrial fibrillation.
Amiodarone develops a Pulmonary fibrosis. Other medications are Bleomycin and Busulfan.
What drugs have cough as a potential side effect?
ACE inhibitors.
A 32-year-old woman presents with several days of worsening bloody diarrhea and abdominal pain. About 2-3 weeks ago the patient was ill with a sore throat for which she received treatment.
What does she have? What causes it?
Pseudomembranous colitis caused by Clindamycin or Amoxicillin/Ampicillin.
What drugs have Focal to massive hepatic necrosis as a potential side effect?
Halothane, Acetominophen, Valproic acid and Amanita Phalloides (mushroom toxin).
What drugs have Hepatitis as a potential side effect?
INH (Isoniazid)
A 66-year-old man presents with a progressive enlarging breast tissue. He has a PMHx of CHF (Chronic Heart Failure). What is the drug?
He has Gynecomastia caused by Spirinolactone. Also is caused by Digoxin, Estrogens, Cimetidine, Chronic alcohol use, Ketoconazole, Marijuana.
What drugs have Adrenocortical insufficiency as a potential side effect?
Withdrawal of corticosteroids.
What drugs have Hot flashes as a potential side effect?
Tamoxifen and Clomiphene.
What drugs have Hypotiroidism as a potential side effect?
Amiodarone, Lithium and Sulfonamides.
A 50-year-old man presents with a swollen, red and painful right first toe. This began spontaneously. He has a PMHx of Diabetes, HTN and Dyslipidemia. What mess are we thinking here?
Gout: Furosemide, Thiazides, Niacin, Cyclosporin, Pyrazinamide.
What drugs have Gingival hyperplasia as a potential side effect?
Phenytoin and Verapamil.
What drugs have Osteoporosis as a potential side effect?
Corticosteroids and Heparin.
What drugs have Photosensitivity as a potential side effect?
Sulfonamides, Amiodarone and Tetracycline.
What drugs have Stevens-Johnson syndrome as a potential side effect?
Seizure drugs: Ethosuximide, Carbamazepine, Lamotrigine, Phenytoin and Phenobarbital.
Sulfa drugs, Penicillin and Allopurinol.
