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DIT Recommended Course Order > Video 4 Sympathetic Inhibition > Flashcards

Video 4 Sympathetic Inhibition Flashcards

1
Q

Which are the alpha1-blockers?

A

Prazosin, Terazosin, Doxazosin and Tamsulosin.

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2
Q

Which are the clinical applications of the Alpha1- blockers?

A

Urinary symptoms of Benign Prostatic Hyperplasia, and. hypertension (Except Tamsulosin).

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3
Q

What are the characteristics of the alpha1-blockers?

A

Decreased blood pressure, cause bladder sphincter relaxation, used to treat BPH.

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4
Q

What are the side effects of the alpha1-blockers?

A

Postural hypotension, reflex tachycardia and rebound hypertension. Also dizziness and headache.

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5
Q

Which of the alpha1-blockers is more selective for alpha1A,D receptors on prostate?

A

Indeed Tamsulosin doesn’t relax vascular Alpha1B receptors and as a result doesn’t low Blood pressure as much.

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6
Q

Which are the Nonselective alpha blockers?

A

Phenoxybenzamine (irreversible) and Phentolamine (Reversible).

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7
Q

What are the applications of phenoxybenzamine?

A

Pheochromocytoma (used preoperatively) to prevent catecholamine (hypertensive) crisis.

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8
Q

What is the alpha2-blocker selective used in Depression?

A

Mirtazapine. Side effects:Sedation, increased serum cholesterol, and increased appetite.

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9
Q

What are the Nonselective B-blockers?

A

Nadolol, Propanolol and Timolol.

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10
Q

Which are the selective B1-blockers?

A

Atenolol, esmolol and metoprolol.

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11
Q

Which are the Weak B1 and B2 agonists? And which are they clinical applications?

A

Acebutolol, Pindolol.

Act as antagonists, and they are used in patients with Hypertension and Bradycardia.

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12
Q

Which are the alpha1/beta1- blockers?

A

Carvedilol and Lavetalol.

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13
Q

What are the B-blockers effects in Angina pectoris?

A

Decreased heart rate and contractility, resulting in low O2 consumption.

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14
Q

What are the B-blockers effects in Myocardial Infarction?

A

B-blockers (metropolol, carvedilol, and bisoprolol) decreased mortality.

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15
Q

What are the B-blockers effects in Supra Ventricular Tachycardia (metoprolol and esmolol)?

A

Decreased AV conduction velocity (class II antiarrhythmic).

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16
Q

What are the B-blockers effects in Hypertension?

A

Decreased cardiac output also decreased renin secretion (due to B1-receptor blockade on JGA cells).

17
Q

What are the B-blockers effects in Chronic Heart Failure?

A

Decreased mortality.

18
Q

What are the B-blockers effects in Glaucoma (Timolol)?

A

Decreased secretion of aqueous humor.

19
Q

Which are the B-blockers applications?

A

Hyperthyroidism, Migraine prophylaxis, Anxiety, Aortic dissection.

20
Q

To which population you will be careful when you used B-blockers?

A

Asthmatics and COPD patients.

21
Q

Which are the adverse effects of the B-blockers?

A
  • Bronchoconstriction.
  • Hypoglycemia.
  • increased hypertension in cocaine user.
  • Rebound tachycardia, hypertension.
  • Arrhythmia.
22
Q

Which are the Partial agonists B-blockers?

A

Acebutolol and Pindolol.

23
Q

Which are the B-blockers used in Glaucoma?

A

Timolol and Nadolol.

24
Q

Which are the alpha2- Adrenergic agonist?

A

Clonidine and Alpha-methyldopa

25
Q

Which are the clinical applications of Clonidine?

A

Malignant hypertension and Sedative.

26
Q

Which are the clinical applications of aloha methyldopa?

A

Hypertension in pregnancy.

27
Q

Which selective alpha-blocker has less effect on blood pressure?

A

Tamsulosin.

28
Q

What are the common side effects of B-blockers? Which patient populations should use caution when taking B-blockers ?

A

Bronchospasm: Use with caution in asthmatics, COPD.
Lower blood glucose and mask sympathetic symptoms of hypoglycemia: Use with caution in diabetics.
Bradycardia, AV block: Use with caution in acute Chronic Heart Failure patients.

29
Q

What are the various clinical applications of B-blockers?

A

HTN, SVT, Angina, MI, Glaucoma.

30
Q

RFF: Medical treatment for Pheochromocytoma.

A

Alpha-antagonist.

31
Q

RFF: Selective alpha1-antagonist used to treat BPH.

A

Tamsulosin.

32
Q

Which of the following drugs is both a alpha-antagonist and beta-antagost? A)Carvedilol. B)Propanolol. C)Terazosin. D)Phentolamine.

A

A)Carvedilol.

33
Q 
Which of the following drugs is Nonselective beta-antagonist?
A)Atenolol.
B)Nadolol.
C)Metoprolol.
D)Esmolol.
A

B)Nadolol.

DIT Recommended Course Order (21 decks)

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