Video 2 Parasympathetic Inhibition Flashcards

1
Q

What drug inhibit parasympathetic activity?

A

Muscarinic antagonists

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2
Q

Which are the uses for Atropin?

A

Bradycardia, Dilate the pupil, Organophosphate poisoning and Enuresis.

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3
Q

What is the clinical application of Benztropin?

A

Parkinson disease and acute dystonia.

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4
Q

What drug is used in COPD and Asthma for its mechanism of action?

A

Ipratropium and triotropium, because they can reduce bronchoconstriction.

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5
Q

Which drug is characterized by reduce bladder spasms and urge urinary incontinence ?

A

Oxybutynin

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6
Q

What are the effects of Scopolamine in CNS?

A

Motion sickness and decreases oral secretions

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7
Q

What anticholinergics are used in the treatment of urge type urinary incontinence?

A
Oxybutynin.
Tolterodine.
Darifenacin  and solifenacin.
Trospium.   
"On The Darn Toilet"
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8
Q

Which is the muscarinic antagonist used in urge incontinence?

A

Oxybutynin

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9
Q

Which is the muscarinic antagonist characterized by bronchodilator effect?

A

Ipratropium and Tiotropium

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10
Q

Which is the muscarinic antagonist used in Parkinson’s disease?

A

Benztropine. Park my Benz

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11
Q

Which is the muscarinic antagonist used in organophosphate poisoning?

A

Atropin.

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12
Q

Which is the muscarinic antagonist is characterized because decrease airway secretions?

A

Scopolamine

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13
Q

Which is the muscarinic antagonist used in urge incontinence?

A

Darfenacin

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14
Q

Which is the muscarinic antagonist used in Motion sickness?

A

Scopolamine

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15
Q

Which is the muscarinic antagonist that produce mydriasis?

A

Tropicamide.

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16
Q

In what patient population is Atropin contraindicated?

A

BPH (Beign Prostatic Hyperplasia), Hyperthermia, Acute-angle glaucoma, Elderly (may cause Delirium), GI obstruction (or ileus)

17
Q

What other medications have anticholinergic side effects?

A

1) First generation H1 blockers (diphenhydramine, chlorpheniramine.
2) Neuroleptics (clozapine).
3) Tricyclic antidepressants.
4) Amantadine.

18
Q

What type of drug is physostigmine?

A

Anticholinesterase.

19
Q

What type of drug is Pilocarpine?

A

Direct cholinergic agonist

20
Q

What type of drug is Oxybutynin?

A

Anti-Muscarinic.

21
Q

What type of drug is Atropine?

A

Anti-Muscarinic

22
Q

What type of drug is Donepezil?

A

Anticholinesterase.

23
Q

What type of drug is Pralidoxime?

A

Cholinesterase regenerator.

24
Q

What type of drug is Bethanechol?

A

Direct cholinergic agonist.

25
What type of drug is Neostigmine?
Anticholinesterase.
26
What type of drug is Darifenacin?
Anti-Muscarinic
27
What type of drug is ipratropium?
Anti-Muscarinic
28
What type of drug is Tropicamide?
Anti-Muscarinic
29
What type of drug is Benztropine?
Anti-Muscarinic
30
What type of drug is Scopolamine?
Anti-Muscarinic
31
What type of drug is Edrophonium?
Anticholinesterase
32
What type of drug is Tolterodine?
Anti-Muscarinic
33
What type of drug is Trospium?
Anti-Muscarinic
34
What type of drug is Rivastigmine?
Anticholinesterase
35
What type of drug is Homatropine?
Anti-Muscarinic
36
What type of drug is Pyrodostigmine?
Anticholinesterase.
37
What type of drug is Carbachol?
Direct cholinergic agonist
38
Which of the muscarinic antagonists discussed could be used to improve FEV1 in a patient with COPD?
Ipratropium and Tiotropium
39
What are the symptoms of inhibiting parasympathetic activity?
Hyperpyrexia, flushing, cycloplegia, mydriasis, lack of salivation, confusion, delirium, constipation, urinary retention. And Tachycardia