Venous thromboembolism Flashcards
2 types of venous thromboembolism VTE
-pulmonary embolism- clot in lungs (PE)
-deep vein thrombosis- thrombus in leg (DVT)
Thrombus-
Embolus-
-blood clot
-anything that moves through a vessel until the vessel gets too small to pass (usually due to a thrombus)
DVT pathophysiology
Thrombosis
-damaged and warped valves
-causes blood to flow in both directions and blood to accumulate in vein
Embolus
-blood moves slowly causing a clot or thrombus to form
-the clot can then break off and travel in blood as an embolus
VTE risk factors and what causes the risk factors
Virchow’s triad thrombosis
1. Hypercoagulability (blood clots easily)- caused by surgery, pregnancy, cancer, infection etc
2. Vascular damage (damage to vessel wall)- cellulitis, atherosclerosis (fat deposits), venepuncture, inflammation
3. Circulatory status- immobility, venous obstruction, varicose veins, atrial fibrillation
Other risks
-over 60
-male
DVT signs and symptoms
-pain/ tenderness
-reddening/ discolouration
-swelling
-difficulty weight bearing
-leg tiredness
Wells scoring for DVT
0-1= low probability of DVT
1-2= moderate probability
3-8= high probability
DVT pathway (different patient groups)
Pregnant or given birth 6 weeks ago- referred for same day assessment
Low to moderate wells score- referred for same day assessment
High wells score- need to be seen within 4 hours
High wells score treatment
-need ultrasound
-if not possible need D-dimer test followed by therapeutic anticoagulation
-advice from GP for direct referral to DVT clinic
Signs of different PE
Multiple small PE- progressive breathlessness, non emergency
Segmental emboli with pulmonary infarction- chest pain, no circulatory compromise
Major PE in larger branches- sudden onset shortness of breath, tachycardia and hypotension
Massive PE- LOC, tachypnoea, can be fatal
Symptoms PE
-dyspnoea
-pleuritic chest pain (sharp, worse on inhalation, localised)
-cough
-haemoptysis (blood in sputum)
-syncope (fainting)
Signs PE
-tachypnoea- greater than 20
-tachycardia- greater than 100
-SPO2 less than 92%
-signs of DVT
-low grade fever
PE pathway
-time critical in primary survey, correct them first eg. blocked airway etc
Not time critical
-specific assessment
-oxygen if needed
-position of comfort, often sitting
-ECG
-pain relief (avoid entonox if one of differentials is pneumothorax, avoid morphine if shocked)
-transfer rapidly to hospital with pre alert