Vecuronium (generic) Flashcards
Description
Nicotinic NMJ blocker (non-depolarizing), reversible competitive inhibition, amniosteroid
Actions
Directly blocks receptors on nicotinic end plate, thereby causing flaccid skeletal muscle paralysis, used in drug cocktail for executions
Indications
Production of complete skeletal muscle relaxation (surgery, etc)
Toxicity
BLACK BOX admin by adequately trained individuals familiar w/ actions, characteristics, and hazards. respiratory failure produces paralysis in fully conscious patients, tachycardia, hypertension, histamine release, ganglionic and muscarinic side effects
Other facts
duration of action 30-60 minutes, neostigmine will reverse action, hepatic impairment, caution advised