Atropine (generic)

Question 1

Description

Answer 1

Non-selective muscarinic receptor blockers

Question 2

Actions

Answer 2

Prevents action of acetylcholine, lowers activity of all muscles and glands regulated by the parasympathetic nervous system

Question 3

Indications

Answer 3

Organophosphate poisoning (insecticide, nerve gas - given with Pralidoxime / 2-PAM), optically for pupil dilation, bradycardia, to reduce secretions

Question 4

Toxicity

Answer 4

Mad as a Hatter (delirium / halucinations)
Blind as a Bat (mydriasis, photophobia, cycloplegia)
Dry as a Bone (block secretions salivary / sweat)
Red as a Beet (fever, anhidrosis, vessel dilation)
Hot as a hare (hyperthermia from anhidrosis)
Urinary retention (block detrusor), bronchodilation, constipation, tachycardia

Question 5

Other Facts

Answer 5

SC; IM; IV; INJ lipid soluble so crosses BBB for when toxins have also crossed B