Pralidoxime (2-PAM) Flashcards
1
Q
Description
A
Reactivates cholinesterase
2
Q
Actions
A
Binds to organophosphate inactivated acetylcholinesterase and accelerates reactivation
3
Q
Indications
A
Cholinesterase inhibitor overdose, organophosphate insecticide poisoning, organophosphate nerve agent poisoning
4
Q
Toxicity
A
When used with atropine, as it usually is, atropine toxicity is enhanced (dry as a bone, hot as a hare, mad as hatter, red as a beet, blind as a bat)
5
Q
Other facts
A
IV / IM only, useful if administered soon after exposure to toxin, military has stockpiles of auto-injectors in case of nerve gas use
