Donepezil (Aricept) Flashcards

1
Q

Description

A

Reversible cholinesterase inhibitor

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2
Q

Actions

A

Indirectly stimulates both nicotinic and muscarinic acetylcholine receptors

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3
Q

Indications

A

Alzheimers associated dementia

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4
Q

Toxicity

A

GI upset

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5
Q

Other facts

A

Crosses the BBB, 100% bioavailability

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6
Q

Other drugs used for Dementia: (2)

A
  1. Rivastigmine (Exelon) - reversible cholinesterase inhibitor patch form - reduces GI upset
  2. Galantamine - Nn agonist and acetylcholinesterase inhibitor
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