Physostigmine (generic) Flashcards
1
Q
Description
A
Reversible cholinesterase inhibitor
2
Q
Actions
A
Indirectly stimulates both nicotinic and muscarinic acetylcholine receptors
3
Q
Indications
A
Glaucoma, Alzheimers disease, delayed gastric emptying, anticholinergic toxicity with CNS effects e.g. atropine overdose, nondepolarizing neuromuscular blockade reversal
4
Q
Toxicity
A
Cholinergic reaction (DUMBBELSS)
5
Q
Other Facts
A
Crosses the BBB so not used for myasthenia gravis (uncharged and lipid soluble), IV / IM