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Cardiovascular System > Vasculitis > Flashcards

Vasculitis Flashcards

1
Q

Name the Non-infectious Vasculitis’

A 
Giant cell arteritis
Takayasu Arteritis
Polyarteritis Nodosa
Kawasaki Disease
Microscopic Polyangitis
Wegener Granulomatosis
Churg-Strauss syndrome
Thromboangiitis Obliterans
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2
Q

Discuss Giant Cell Arteritis

A
  1. Affects large vessels
  2. Granulomatous inflammation
  3. ‘Patchy’ nodular intimal thickening w/ stenosis
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3
Q

How is Giant Cell arteritis diagnosed?

A

Biopsy

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4
Q

Discuss Takayasu Arteritis

A
  1. Affects Large vessels and Granulomatous inflammation
  2. Mostly Pulmonary Arteries
  3. Patient is younger than 50
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5
Q

Discuss Polyarteritis Nodosa

A
  1. Affects small to medium arteries
  2. No association with ANCA
  3. Transmural inflammation
  4. Lesions of different ages
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6
Q

Which vasculitis is associated with Hep B?

A

Polyartertiis Nodosa

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7
Q

Discuss Kawasaki Disease

A
  1. Acute febrile illness
  2. Autoantibodies to endothelial cells and smooth muscle
  3. Transmural inflammation
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8
Q

Symptoms of Kawasaki Disease

A
  1. Conjunctival and oral edema

2. Edema of hands and feet

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9
Q

Symptoms of Giant cell arteritis

A

Facial pain, ocular symptoms

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10
Q

Discuss Microscopic Polyangitis

A
  1. Small vessels (Capillaries)
  2. Fragmented neutrophils
  3. NO granulomatous inflammation
  4. All lesions are same age
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11
Q

What is associated with Microscopic Polyangitis?

A

MPO-ANCA

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12
Q

How do you treat Giant cell arteritis

A

Steriods

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13
Q

Discuss Wegner Granulomatosis

A

Granulomas of lung or upper airway
Vasculitis (small-medium vessels)
Glomerulonephritis

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14
Q

What is associated with Wegner Granulomatosis?

A

PR3-ANCA; Can be used as a marker for activity as well as diagnosis

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15
Q

Discuss Churg-Strauss Syndrome

A

Small vessel necrotizing vasculitis

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16
Q

What is associated with Churg-Strauss Syndrome?

A
  1. Asthma
  2. Eosinophilia
  3. CM
17
Q

Discuss Thromboangitis Obliterans

A
  1. Usually involves the tibial and radial arteries

2. Heavy smoking history

18
Q

What organisms are responsible for infectious vasculitis

A

Aspergillus and Mucor; Pneumonia

19
Q

What are the symptoms of Microscopic Polyangitis?

A
  1. Necrotizing glomerulonephritis

2. Pulmonary capillaritis

20
Q

What are the symptoms of Thromboangitis Obliterans?

A
  1. Gangrene of extremities

2. Raynaud phenomenon

21
Q

What are the overall symptoms of vasculitis?

A

Fever, Malaise, Myalgia

Cardiovascular System (33 decks)

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