Vaccines & Viral Infections Flashcards

1
Q

passive immunisation is conferred by giving a person

A

antibodies

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2
Q

with passive immunisation, protection is usually … as the persons’ … is not involved

A

short-lived

immune system

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3
Q

In active immunisation, what inititates the persons own defence to mount a response

A

vaccine

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4
Q

acitve immunity may last for …. , but … may be required

A

life

boosters

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5
Q

whole cell vaccines include

A

the whole of the bacterium or virus

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6
Q

subunit vaccine have been developed that contain

A

part of the organism that is known to trigger and immune response

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7
Q

toxoids are ….

A

subunit vaccines

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8
Q

in life-attenuated vaccines, the bacterium or virus is still viable but it is

A

weakend

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9
Q

some life-attenuated viruses can regain their

A

virulence

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10
Q

inactivated vaccines contain

A

viruses or bacteria that have been exposed to denaturing agent such as formaldehyde

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11
Q

in general which sort of vaccines give longer lasting immunity

A

Live vaccines

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12
Q

4 methods of delivering a vaccine:

A

injection
oral
intranasal
in food

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13
Q

Why vaccinate? (3)

A

disease had serious potential outcomes
where disease is common
where no other treamtent is available or less optimal

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14
Q

vaccination is cheaper than …. and … of same disease

A

diagnosis

treatment

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15
Q

vaccination breaks the … cycle

A

transmission

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16
Q

2 targeted childhood vaccinations

A

TB

Hep B

17
Q

what is targeted vaccinations

A

protecting those at higher risk

18
Q

Herd immunity

A

a form of vaccination that occurs when a significant enough number of the population is vaccinated to provide a measure of protection to those in the population who havent been vaccinated

19
Q

risks of vaccination

A

pain at injection site
fever and fatigue following vaccination
occasional rashes
anaphalyctic shock (passive immunisation)

20
Q

vaccine production methods (4)

A

cultivation (numbers up)
purification (isolate what we want)
inactivation (if necessary)
fractionation (produce subunits for vaccination)