Normal microbiota & Disease Flashcards
sterile sites in body free of microbiota
Brain
cerebro-spinal fluid
blood
muscles
3 benefits of normal microbiota
inhibit pathogens
induce antibodies
produce vitamins
3 harmful effects of normal microbiota
potential to cause disease
bacterial synergism
potential to pass to susceptible hosts
Propionibacteriun acnes surive in …
the are gram +ve/-ve lipophilic …
breaks down secreted … to free …
oil glands
+ve rods
lipids
fatty acids
where is largest microbial population in body?
colon
Parasatism:
relationship where symbiont harms or lives at expense of host
pathogen
organism that causes disease
Pathogenicity
ability to cause disease
virulence
intensity of pathogenicity
infection
growth of parasitc organism in host, may or may not lead to disease
5 ways antibiotics stop pathogens
inhibit: peptidoglycan synthesis membrane integrity nucleic acid synthesis protein synthesis metabolism