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Year 1 POD > Blood Basics > Flashcards

Blood Basics Flashcards

1
Q

Content of blood

A

RBCs
WBCs
Platelets
Plasma

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2
Q

Cells occupy what pecentage of total volume?

A

40%

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3
Q

In 70kg male, how many litres of blood, how many red cells, how long do they survive for?

A

5 litres of blood
2.5x10^12
120 days

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4
Q

What is haematopoiesis?

A

Formation of blood cells

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5
Q 
Sites of Haematopoiesis:
0-2 months,
2-7 months,
5-9 months,
Infant,
Adult.
A 
Yolk sac,
liver,
spleen,
marrow,
verterbrae, rib, sternum
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6
Q

Most common cells in blood

A

RBCs

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7
Q

How many in 1ml of blood?

A

4-5 million

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8
Q

Why are RBCs bioconcave

A

Surface area + flexibility

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9
Q

Where are RBCs removed

A

Spleen

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10
Q

What does haemoglobin consist of?

A

4 globin chains

each has one Fe which contains the haem group

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11
Q

How many 02 molecules can one haem group carry?

A

4

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12
Q

What is erythropoiesis

A

Production of blood after signalling from kidney to bone marrow.

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13
Q

How many WBCs per litre

A

5x10^9

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14
Q

Name all types of WBCs

A 
Neutrophils
Eosinophils
Basophils
Monocytes
Lymphocytes
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15
Q 
Neutrophils: 
What % of WBCs?
Lifespan?
Defence mechanism (specific/non-specific)
How long can survive in tissues?
Lobing
A 
60%
6-10hrs
non-specific
few days
Lobed
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16
Q 
Eosinophils:
% of WBCs
Lobing
circulation time
Defence
A

1%
Bilobed Nucleus
parasitc defence + allergies
4-5 hours

17
Q

Basophils:
% of WBCs
Defence

A

<1%

Inflammatory

18
Q 
Monocytes:
% of WBCs
Smallest or Biggest
Circulation time
Mature into...
Function
A 
5%
Biggest
circulate for 10 hours, then move to tissues
Macrophages
remove RBCs
19
Q 
Lymphocytes:
% of WBCs
Nucleus shape & size
Lifespan
Defence
A

33%
Round, Large
variable
specific, receptors on surface

20
Q

T-Lymphocytes:
Develop in…
Responsible for…

A

Thymus

Cell-mediated immunity

21
Q

T-helper cells:

Secretes ……. which activates…..

A

Cytokines

Killer cells

22
Q

T Cytotoxic are

A

Killer Cells

23
Q

B-Lymph cells:
Derived from…
produces…

A

Bone Marrow

antibodies

24
Q

Natural Killer Cells:

defence, (3 parts)

A

non-specific
viral
cancer defence

25
Q

Platelets (Thrombocytes):
responsible for…
life span

A

blood clotting, arrest of blood loss

10-12 days

26
Q

Plasma:
Carries
regulates
Is always electrically +ve -ve or neutral

A

electrolytes, proteins
osmotic balance
neutral

Year 1 POD (20 decks)

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