Inflammation Flashcards
acute inflammation lasts for….
minutes/days
chronic inflammation last for…
months/years
rubor (redness) is caused by
increased blood flow
calor (heat) is caused by
vasolidation
tumour (swelling) is caused by
increased blood vessel permeability (exudate)
inflammatory processes can be divided into… (3)
vascular changes
cell mediators
cellular response
3 vacular changes in inflammatory process
increased blood flow
increased permeability
migration of leukocytes
protein rich fluid that passes into tissue is called
exudate
pus is a specific type of ….. containing
exudate
dead bacteria and leucocytes
name process of cells following concentration gradient to reach site of inflammatory response
chemotaxis
prostaglandins are a target for … and are responsible for
non-steroidal anti-inflammatory drugs
vasilodation and pain
HIstamine and serotonin are released due to …..
, they are a target for…. and are responsible for
physical trauma or immunological reaction
anti-histamine drugs
vasolidation and increased permeability
HIstamine and serotonin are released due to …..
, they are a target for…. and are responsible for
physical trauma or immunological reaction
anti-histamine drugs
vasolidation and increased permeability
platelet activating factor causes the aggregation of….,
and is responsible for (3)
platelets
pain, vasolidation, gathering of immune cells
Kinin system is the most powerful ….., also responsible for
vasolidator
increased permeability and pain
complement system is a cell …. system,derived from membrane of ….., responsible for
mediator
neutrophils
increased permeability and cell recruitment
clotting and fibrinolytic system is important in both … and …. fibrinopeptides increase….. is responsible for
clotting and inflammation
vascular permeability
increased permeability and cell recruitment
beneficial effects of inflammation (2)
destructive of infectious organisms
removal of dead cells
deleterious effects of inflammation
risk of severe inflammatory response
in accute inflammation, exudate in rich in
neutrophils
main cells present in chronic inflammation are (3)
lymphocytes macrophages plasma cells
4 causes of chronic inflammation
progression of acute inflammation
recurrent acute inflammation
transplant rejection
rejection of infection to phagocytosis
granulomatous inflammtion is the response to agents that are …..macrophages form discrete cluster called…. these form when system attempts to …. things that it can eliminate
difficult to destroy
granulomas
wall off
granulomatous inflammtion is the response to agents that are …..macrophages form discrete cluster called…. these form when system attempts to …. things that it can eliminate
difficult to destroy
granulomas
wall off
3 main stimuli for granulomatous inflammation
fungi
non-livng material deposited in tissue
microorganisms of low pathogenicity, but excite immune response
scarring is causes by myofibroblasts depositing … in the wound
collagen
