Inflammation Flashcards

1
Q

acute inflammation lasts for….

A

minutes/days

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2
Q

chronic inflammation last for…

A

months/years

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3
Q

rubor (redness) is caused by

A

increased blood flow

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4
Q

calor (heat) is caused by

A

vasolidation

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5
Q

tumour (swelling) is caused by

A

increased blood vessel permeability (exudate)

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6
Q

inflammatory processes can be divided into… (3)

A

vascular changes
cell mediators
cellular response

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7
Q

3 vacular changes in inflammatory process

A

increased blood flow
increased permeability
migration of leukocytes

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8
Q

protein rich fluid that passes into tissue is called

A

exudate

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9
Q

pus is a specific type of ….. containing

A

exudate

dead bacteria and leucocytes

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10
Q

name process of cells following concentration gradient to reach site of inflammatory response

A

chemotaxis

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11
Q

prostaglandins are a target for … and are responsible for

A

non-steroidal anti-inflammatory drugs

vasilodation and pain

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12
Q

HIstamine and serotonin are released due to …..

, they are a target for…. and are responsible for

A

physical trauma or immunological reaction
anti-histamine drugs
vasolidation and increased permeability

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13
Q

HIstamine and serotonin are released due to …..

, they are a target for…. and are responsible for

A

physical trauma or immunological reaction
anti-histamine drugs
vasolidation and increased permeability

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14
Q

platelet activating factor causes the aggregation of….,

and is responsible for (3)

A

platelets

pain, vasolidation, gathering of immune cells

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15
Q

Kinin system is the most powerful ….., also responsible for

A

vasolidator

increased permeability and pain

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16
Q

complement system is a cell …. system,derived from membrane of ….., responsible for

A

mediator
neutrophils
increased permeability and cell recruitment

17
Q

clotting and fibrinolytic system is important in both … and …. fibrinopeptides increase….. is responsible for

A

clotting and inflammation
vascular permeability
increased permeability and cell recruitment

18
Q

beneficial effects of inflammation (2)

A

destructive of infectious organisms

removal of dead cells

19
Q

deleterious effects of inflammation

A

risk of severe inflammatory response

20
Q

in accute inflammation, exudate in rich in

A

neutrophils

21
Q

main cells present in chronic inflammation are (3)

A

lymphocytes macrophages plasma cells

22
Q

4 causes of chronic inflammation

A

progression of acute inflammation
recurrent acute inflammation
transplant rejection
rejection of infection to phagocytosis

23
Q

granulomatous inflammtion is the response to agents that are …..macrophages form discrete cluster called…. these form when system attempts to …. things that it can eliminate

A

difficult to destroy
granulomas
wall off

24
Q

granulomatous inflammtion is the response to agents that are …..macrophages form discrete cluster called…. these form when system attempts to …. things that it can eliminate

A

difficult to destroy
granulomas
wall off

25
Q

3 main stimuli for granulomatous inflammation

A

fungi
non-livng material deposited in tissue
microorganisms of low pathogenicity, but excite immune response

26
Q

scarring is causes by myofibroblasts depositing … in the wound

A

collagen