Uworld Practice Test 1 Flashcards

1
Q

ARDS is caused by injury to?

A

Endothelial Lining

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2
Q

Paget’s disease of the bone is associated with?

A

Osteosarcoma

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3
Q

Lump in the throat is?

A

Globus hystericus

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4
Q

What vitamin is tetratogenic?

A

vitamin A

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5
Q

Oseltamivir (Tamiflu) MOA? Use?

A

MOA: inhibits neuroamindase of influenza A and B
Use: Early treatment and prevention of influenza

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6
Q

Cells varying in length and time show?

A

Posttranslational modification

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7
Q

Fragmentation in multiples of 180 base pairs. What is this called?

A

DNA Laddering

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8
Q

Where is DNA laddering found?

A

During Karrhyrexis in Apoptotic cells

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9
Q

Why is DNA laddering used?

A

To distinguish between apoptotic cells and necrotic cells

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10
Q

Physgiostigimine fights?

A

Atropine

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11
Q

Benzodiazpine AE?

A

confusion

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12
Q

When a genetic mutation is identified in the offspring but not the parents?

A

Germline Mosaicism

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13
Q

DM patients should always do what every day?

A

Foot Ulcer

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14
Q

IL-1, TNF-alpha, IL-6 is primarily produced by? What are they produced in response to?

A

Mononuclear phagocytes/Marcrophages

Inflammation

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15
Q

What is Ca2+ dependent and connects intercellular adhesions?

A

Cadherins

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16
Q

Low pH of udodenal content triggers release of?

A

Bicarb

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17
Q

Posterior displacement of the tibia? What artery is affected?

A

popliteal artery

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18
Q

Foul Smelling Discharge after a vaginal delivery? Agent?

A

Endometritis

Bacteriodes

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19
Q

Person channels socially unacceptable impulses to acceptable impulses (like channeling abuse to basketball)

A

Sublimation

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20
Q

Tyrosine Kinase auto?

A

phosphorylates and dimerizes

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21
Q

Physician repeats what patient has told him? Defense mechanism?

A

Reflection

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22
Q

Physician encourages patient to talk more about a technique?

A

facilitation

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23
Q

Individual attributes thoughts and feelings to another person

A

projection

24
Q

Headache, chronic nasal discharge and atrophic septum?

A

Cocaine absuer

25
Heminephrectomy changes GFR from what to what?
50%=>80%
26
When she pushes against a wall with outstreched arms, there is prominence of the right scapular angle? What nerve and muscle is involved?
Winged Scapula SALT (serratus anterior and Long thoracic n.)
27
ATSD vs PTSD Difference?
>4 weeks PTSD
28
Schizophrenia symptoms?
Delusions, hallucinations, disorganized speech or negative symptoms
29
Schizophrenic symptoms for 1-6 months
Schizophreniform symptoms
30
Schizophrenic symptoms for >6 months
Schizophrenia
31
Schizophrenic symptoms
Brief Psychotic episodes
32
Relative Risk?
Exposed Risk/Unexposed Risk
33
Number needed to treat is opposite of the?
absolute risk reduction value
34
Absolute Risk Reduction?
Percentage of mortality in Conventional-Percentage of mortality in Novel
35
Headache, altered level of consciousness and increased signalling in the temporal lobe?
Encephalitis
36
MCC of viral Encephalitis?
HSV
37
MC Porphyria?
Porphyria cutanea tarda
38
Acute Intermittent Porphyria, enzyme and accumulation?
Hydroxymethylbilane (HMB) synthase | Porphobilinogen
39
Porphyria Cutanea Tarda, enzyme and accumulation?
URO decarboxylase | Uroporphyrinogen
40
What diseases have Anticipation?
Trinucleotide repeat diseases
41
Recurrent hemathroses?
Hemophilia
42
Hemophilia Genetics?
X-linked
43
Exudate vs transudate fluid
Exudate | Protein>0.5 and Pleural LDH>0.6
44
Hemolysis in buffered salt solutions?
Osmotic Fragility
45
Hereditary Sphercytosis Labs?
Increased MCHC, acidified glycerol test | abnormal eosin 5
46
Complications of hereditary sphercytosis
Gallstones and aplastic anemia
47
An elderly alcholic with Shock-like sensation that radiates to the feet and neck, what vitamin def.?
B12
48
B12 vs Folate deficiency?
Folate does not induce neurologic symptoms
49
A young patient with difficulty chewing, seeing, What is wrong in this patient?
MG
50
Which is more common Hyperplastic Tissue vs Thymoma?
Hyperplastic Tissue
51
How many genes need to deleted in tumor supressor genes? What is this phenomenon called? Examples?
2 2 hit hypothesis Retinoblastoma
52
Recurrent Fungal or Viral infections suggest problems in?
T-Cell lymphocyte
53
Digeorge Syndrome is the failure of the development of?
3rd and 4th pouch
54
Metabolics associated with DKA?
Metabolic Acidosis, Hyperkalemia, Hyperglycemia, Hyperammoniemia, Hyponatremia
55
In pheochromocytoma, what drug should you use?
Phenoxybenzamine