Uworld Exam 11

Question 1

MC pituitary adenoma in a child?

Answer 1

craniopharyngioma

Question 2

Anterior pituitary origin?

Answer 2

Rathke’s pouch

Question 3

Posterior pituitary origin?

Answer 3

neuroectoderm

Question 4

Craniopharyngioma contains 3 components?

Answer 4

Solid, cystic, calcification

Question 5

Another word for urge incontinence? MOA?

Answer 5

Gotta Go!

MOA: destrusor muscle instability (overactive bladder)

Question 6

A patient who has an urge to urinate and cannot make it to the bathroom and pees on herself? Tx?

Answer 6

urge incontinence

Tx: Antimuscarinics

Question 7

Tricuspid valve is heard best at?

Answer 7

4th ICS at the lower sternal border (parasternal)

Question 8

Synthesis of multiple, short DNA fragments?

Answer 8

Okazaki Fragments

Question 9

A patient with Excessive Daytime Sleepiness and Laughter/crying triggers paralysis. Dx? What is undetectable/low in the CSF of this patient?

Answer 9

Narcolepsy

CSF: Hypocretin-1

Question 10

Where is Hypocretin made and what does it do?

Answer 10

Location: Lateral hypothalamus
Function: promote wakefulness and inhibit REM sleep

Question 11

A patient feels that the physician resembles his dad in that he was not there for him. Dx?

Answer 11

Transference

Question 12

Occurrence of multiple phenotypes often in different organ systems as a result of a single genetic defect?

Answer 12

Pleiotropy

Question 13

Proportion of individuals who express the associated phenotype

Answer 13

Penetrance

Question 14

Hib vaccine is composed of what? What is it attached to?

Answer 14

capsular polysaccharide

Diptheria/Tetanus

Question 15

Haemophilus inflenzae type b causes what particular disease?

Answer 15

meninigitis

Question 16

Obstructive sleep apnea can lead to what two manifestations?

Answer 16

Pul. HTN and R. Heart Failure

Question 17

Pulsatile Treatment of GnRH is for?

Answer 17

Infertility

Question 18

Most Hypoosmolar in the nephron?

Answer 18

Early Distal Tubule

Question 19

Aortic Regurgitation Murmur is best heard where?

Answer 19

Left Sternal Border, patient leaning forward and on expiration

Question 20

Liver Biopsy shows pigmented inclusions in the lysosomes and the pigments are polymers of epinephrine. What disease?

Answer 20

Dubin Johnson

Question 21

Dubin Johnson pathogenesis?

Answer 21

defective hepatocellular excretion of bilirubin glucuronides

Question 22

1 standard deviation equals?

Answer 22

68%

Question 23

During a urine deprivation test, a primary polydipsic patient will exhibit what kind of urine osmolarity?

Answer 23

significant increase in urine osmolality

Question 24

Sublingual Table for Angina?

Answer 24

Nitrates

Question 25

What Ig crosses placenta?

Answer 25

IgG

Question 26

Down Syndrome Disjunction?

Answer 26

Nondisjunction in maternal meiosis I

Question 27

Glucocorticoid therapy can lead to entire shunt down of the HPA axis which can lead to?

Answer 27

adrenal insufficiency (MC)

Question 28

Eosinophils two MOA?

Answer 28

1. Parasite: IL-5 via Th2 to parasites, major basic protein and ADCC 2. Type 1 HSR cytokine production

Question 29

Mucicarmine stain is used to detect?

Answer 29

C. Neoformans

Question 30

Cryptococcus most common presentation?

Answer 30

meningoencephalitis

Question 31

PABA esters are used to absorb?

Answer 31

UVB

Question 32

1st line for depression?

Answer 32

SSRI

Question 33

Precursor of serotonin?

Answer 33

tryptophan

Question 34

Antidote to serotonin syndrome?

Answer 34

Cyproheptadine

Question 35

VZV lacks what kinase?

Answer 35

thymidine kinase

Question 36

A large mass after a tooth extraction?

Answer 36

Actinomyces israelii

Question 37

Tx for actinomyces israelii?

Answer 37

Penicillin

Question 38

Apical Lung Tumors called? What syndrome can they produce?

Answer 38

Pancoast Tumors | Horner's Syndrome

Question 39

A patient with pain is given an opioid and it causes a abdominal pain. What is this called?

Answer 39

Biliary Colic=>constriction of sphincter of oddi

Question 40

Tet Spells are seen in patients with?

Answer 40

Right to Left Shunts

Question 41

Preeclampisa has what three things?

Answer 41

HTN, Proteinuria, edema

Question 42

MC thyroid cancer?

Answer 42

Papillary thyroid Cancer

Question 43

Bx shows large cells with nuclei containing finely dispersed chromatin with ground glass appearance. What is this and where is it found?

Answer 43

Orphan Anne Eyes | Found in Papillary thyroid cancer

Question 44

Septic Arthritis Prophylaxis while waiting for results?

Answer 44

Ceftriaxone

Question 45

Bilateral renal agenesis leads to?

Answer 45

Potter's Syndrome

Question 46

What do potter's syndrome patients most often die of?

Answer 46

Lung Immaturity

Question 47

Epidural hematoma is found between?

Answer 47

Bone and dura mater

Question 48

Epidural hematoma CT?

Answer 48

Biconvex, Lens

Question 49

Subdural Hematoma CT?

Answer 49

Crescent shaped

Question 50

Subarachnoid CT?

Answer 50

Blood in basal cisterns

Question 51

Hashimoto Thyroiditis Bx?

Answer 51

Mononuclear, parenchymal infiltration with well developed germinal centers

Question 52

Serotonin Syndrome symptoms?

Answer 52

After treatment with a SSRI or SNRI, you get myoclonus, flushing, diarrhea