Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Uworld > Uworld Exam 14 > Flashcards

Uworld Exam 14 Flashcards

1
Q

Gag protein on HIV is? What does it encode for?

A

Gp 24

Capsule

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Env protein on HIV is?

A

Gp 120, Gp41

Envelope=>to absorb the virion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Pol Protein on HIV is?

A

Reverse Transcriptase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

CEA is for?

A

Tumor Recurrance

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Suppressed with Dexamesthone?

A

Pituitary Adenoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Not Suppressed with Dexamesthone?

A

Ecotopic ACTH production

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Suppressed ACTH Levels?

A

Adrenal Adenoma/Exogenous Glucocorticoids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

With Inhaled Corticoidsteroids, watchout for?

A

Oral Candidasis

Oral Rinse

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Most Preventable cause of death?

A

Smoking

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Ways to prevent mortality? What is #1 and #2

A 
#1=stop smoking
#2=aspirin therapy
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Infant with poor feeding, increased head circumference and enlarged ventricles on CT?

A

Hydrocephalus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Long term complication of Hydrocephalus?

A

Hypertonicity and hyperreflexia due to Upper Motor Neuron Lesion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

consists of two immunoglobulin monomers, J chain and secretory component. What is the immunoglobulin?

A

IgA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Ureteral Constriction decreases?

A

GFR and FF

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

How do you check for Menopause?

A

FSH and estradiol levels NOT LH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Actin attaches to?

A

An Interesting Zoo
Must Have Mammals

Actin I-Band to the Z line
Myosin H-band to the M-line

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Sun Exposure leads to? How do you fix it? When does this occur?

A

DNA damage via pyrimidine dimers
Endonuclease nicking of the damaged DNA strand
G-1 phase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Ataxia-Telangiectasia MOA? You bring it together via?

A

MOA: 2 ds DNA breakage
Repair: Non-homologous end joining

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Base Excision Repair MOA?

A

MOA: Base specific glycoylase removes altered base and creates AP site
Occurs throughout the cycle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Mismatch Repair occurs in what disease? When does this occur?

A

HNPCC

G-2 phase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

PAO2 equation?

A

150-PaCO2/0.8

22
Q

Enoxaparin MOA

A

MOA: Binds to antithrombin to inhibit to factor Xa

23
Q

Fondaparinux MOA

A

MOA: Xa Inhibitor

24
Q

Unfractionated Heparin MOA

A

MOA: Binds to antithrombin to inhibit Factor Xa and Thrombin

25
Zona fasciulata secretes?
cortisol
26
Zona Reticulata secretes?
Androgen
27
3 SD equals?
99.7%
28
CN 9 innervates
Somatic: Stylopharygneus Parasymp: Otic Ganglion=>parotid gland secretion Sensation: tympanic membrane, eustachian tube, tonsillar region, upper pharynx (gag reflex afferent) Others: carotid sinus and body
29
DOC for malaria? If resistant, next line of choice?
DOC: chloroquine | Next in line: Mefloquine
30
Difficulty walking with a history of diarrhea?
Guian Barre Syndrome with Camplyobacter (MC)
31
After infusion of nitroprusside, patient feels lethargic and confused, lactic acidosis and bright red venous blood, what happened?
CN toxicity
32
How do you treat CN Toxicity?
Sodium Nitrite=>makes it into methemoglobinemia Sodium Thiosulfate=>Sulfur donating to change cyanate to thiocyanate Hydroxycobalamin=>forms cyanocobalamin to be excreted
33
Increased erythrocyte mass, facial pleothra, splenomegaly?
Polycythemia Vera
34
Polycythemia vera has a mutated what pathway?
JAK2
35
JAK2 is what kind of receptor
Cytoplasmic tyrosine kinase
36
1st line for antiemetic therapy?
5-HT3 antagonist=>ondanstreon
37
Vancomycin MOA AE?
MOA: Blocks glycopeptide polymerization by binding tightly to D-ALA, D-ALA AE: Redman syndrome, Nephrotoxicity
38
Daptomycin MOA AE?
MOA: depolarization of cellular membrane AE: muscle pain, inactivated by pulmonary surfactant
39
Linezolid MOA AE?
MOA: Inhibits bacterial protein syntehsis by binding to the 50s subunit AE: Thrombocytopenia, Optic Neuritis, Serotonin Syndrome
40
MCC of aseptic meningitis
Enterovirus
41
Amyloid associated with Alzheimer's is?
AB amyloid
42
AB amyloid is made by what gene?
APP
43
AB amyloid can lead to?
Amyloid angiopathy
44
Isonazid Resistance?
Non expression of catalase peroxidase
45
In primary renal insuffiency what will the lab values be for Na, K, Cl and Bicarb
Na=down K=up Cl=up Bicarb=down
46
EHEC produces a toxin that is most similar to?
Shigella
47
Excessive worrying for over?
6 months
48
MEN2A
Medullary Thyroid Cancer, Pheochromoctyoma and parathyroid
49
What gene is affected in MEN 2A and 2B?
RET
50
Medullary Thyroid Cancer Histology?
polygonal cells with extracellular amyloid deposits

Uworld (27 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions