Uterine Pathology Flashcards
In the secretory phase, endometrium has a coiled corkscrew appearance. secretes glycogen. More tortuous (turns and twists)
ycauses
causes of bleeding in adolescence/early reproductive life/
DPEB - DUB, pregnancy/ectopic, endometritis, bleeding disorder
reproductive perimenopause?
HYPERPLASIA, ENDOMETRITIS,LEIOMYOMA,POLYP,PREGNANCY,ADENOMYOSIS, EXOGENOUS HORMONES, DUB, BLEEDING DISORDERS, NEOPLASIA
post menopause?
bleeding disorder, exogenous hormones, endometritis, polyp, cancer
TVUS is an endometrial thickness of >4mm post menopausal and >16 pre menopausal. It is taken as an indication for?
biopsy
what is the most thorough sampling method for endometrium
dilation and curretage
which condition do you get at ends of reproductive life, corpus lute doesn’t form, and get continued growth of the functionalis layer?
DUB
in ovulatory, what is the problemm?
corpus lute doesn’t produce enough progesterone
glands and storm continue to grow. last mensrual period was 8 weeks ago
DUB
what protects the endometrium from ascending infection?
cervical mucus plug
what makes the endometrium relatively resistant to infection?
constant shedding
causes of endometritis?
either microorganisms or inflammation
which micro organisms cause endometritis?
neisseria, chlamydia, TB, CMV, actinomyces, HSV
what sort of inflammation?
IUCD, post curettage, post partum/abortal, chronic endometritis, granulomatous,
chronic plasmacytic endometritis is ________until proven otherwise
infective
common around menopause, usually asymptomatic, may present with bleeding or discharge
polyp
polyps are almost always benign
y
trophoblastic disease which grows as a mass characterised by SWOLLEN chorionic villi?
molar pregnancy
how can they be divided?
partial or complete
how do these come about?
sperm combine with an egg which has no DNA
only paternal DNA is present in a complete mole
y
in a partial mole, 1 egg is fertilised by?
2 sperm
which moles are at higher risk of developing in to a choriocarcinoma?
complete
what is adenomyosis?
endometrial glands and storm within the myometrium
when would you get this?
perimenopausal (only one with a)
causes bleeding, menorrhagia and dysmenorrhoea
y
leiomyoma. pain, pressure symtoms, tenderness, smooth echogenic mass on US, can be single or multiple, commonest cause of pelvic mass. what are they dependant on for growth
oestrogen
