physiology of pregnancy and lactation Flashcards
fertilised egg develops and differentiates into a
blastocyte
transport into uterus on day ?
3-5
attaches to lining ofuterus on day?
5-8
blastocyst - inner cells develop into embryo, outer cells burrow into uterine wall and become placenta. what does the placenta produce which maintains pregnancy>
hormones
blastocyst lined by?
trophobalst cells
when blastocyst adheres to the endometrial lining, chords of trophoblastic cells….?
begin to penetrate into the endometrium
advancing chords of trophoblastic cells tunnel deeper into the endometrium, carving a hole for the blastocytes
when implantation is finished, blastocyst is completely buried in endometrium
completely delved by?
day 12
placenta is derived from both …cells and …cells
trophoblastic and decidua
trophoblast cells differentiate into multinucleate cells, (syncytiotrophoblasts), which invade decidua and break down capillaries to form cavities filled with maternal blood
y
what does the developing embryo do?
sends capillaries into the syncytiotrophoblastic projections to form placental villi
placental villi - separate maternal blood and fetal blood by thin layer of tissue. is there exchange?
no
when is the placenta functional by?
5th week of pregnancy
early nutrition of the embryo?
invasion of the trophoblastic cells into the decieua
hcg signals the corpus luteum to continue secreting?
progesterone
progesterone stimulates the endometrium to concentrate which substances?
glycogen, protens and lipid
as placenta develops, it extends hair like projections into the uterine wall
this increases contact area between the uterus and placenta
a thin membrane separates fetal blood from maternal blood. what is the space called between this>
intervillous space
the placenta plays the role of?
fetal lungs
exchange takes place between maternal (oxygen rich blood) and umbilical cord (arterial and venous blood)
y
oxygen rich blood travels to the fetus via the?
umbilical vein
maternal oxygen poor blood travels back into the ?
uterine veins
deoxygenated blood from fetus..pathway?
umbilical arterIES - (maternal) uterine vein
3 factors which facilitate oxygen supply to the fetus?
fetal haemoglobin has an increased ability to carry 02, have more haemoglobin, 3 = bohr effect (fetal hb can carry more oxygen in low PC02)