URI pharm - Exam 1B

Question 1

what class is Diphenhydramine
(Benadryl)

Answer 1

H1 blocker (sedating)

Question 2

H1 blocker (sedating) MOA

Answer 2

Bind to H1 receptors & block histamine release

Question 3

Diphenhydramine (Benadryl) indication

Answer 3

Mild allergic reactions, motion sickness, insomnia, severe anaphylactic reactions

Question 4

Diphenhydramine (Benadryl) SE

Answer 4

Drowsiness
Dizziness
Dry mouth
Urinary retention
Constipation

Question 5

Diphenhydramine (Benadryl) nursing consideration

Answer 5

Contraindications: closed angle glaucoma, cardiac disease, kidney disease, hypertension, bronchial asthma, COPD, PUD, seizures, BPH, & pregnancy (we are concerned about drug causing HTN)

Monitor closely for dizziness w/ ambulation

Avoid driving & activities that require alertness

Question 6

what class are Ioratadine (Claritin), Fexofenadine (allegra) and Cetirizine (Zyrtec)

Answer 6

H1 blocker (non sedating)

Question 7

H1 blocker (non sedating) MOA

Answer 7

Bind to H1 receptors & block histamine release

Question 8

Ioratadine (Claritin), Fexofenadine (allegra) and Cetirizine (Zyrtec) indications

Answer 8

Allergic rhinitis, chronic idiopathic urticaria

Question 9

Ioratadine (Claritin), Fexofenadine (allegra) and Cetirizine (Zyrtec) SE

Answer 9

little to no side effects

Question 10

Ioratadine (Claritin), Fexofenadine (allegra) and Cetirizine (Zyrtec) nursing considerations

Answer 10

Contraindications: closed angle glaucoma, cardiac disease, kidney disease, hypertension, bronchial asthma, COPD, PUD, seizures, BPH, & pregnancy (we are concerned about drug causing HTN)

Question 11

what class are Phenylephrine and Pseudoephedrine

Answer 11

Sympathomimetics (decongestant)

Question 12

Sympathomimetics (decongestant) MOA

Answer 12

Mimics the action of SNS by activating alpha 1 adrenergic receptors causing vasoconstriction of blood vessels, causing nasal turbinates to shrink and open nasal passages

“dries you up”

Question 13

Phenylephrine and Pseudoephedrine indication

Answer 13

Reduce nasal congestion, allergic rhinitis, sinusitis, the common cold

Question 14

Phenylephrine and Pseudoephedrine SE

Answer 14

Agitation
Insomnia
Anxiety
Tachypnae
Heart palpitations
all bc of CNS stim

Question 15

Phenylephrine and Pseudoephedrine nursing considerations

Answer 15

Do not use for more than 4 days & tapper off or will get rebound congestion

Sudafed has potential for abuse

Question 16

what class are Dextromethorphan, Codeine
and Benzonatate

Answer 16

antitussive

Question 17

Dextromethorphan, Codeine
and Benzonatate indication

Answer 17

Cough (acute or chronic)

Question 18

antitussive MOA

Answer 18

Directly suppresses the cough reflex in the brain

Question 19

Dextromethorphan, Codeine
and Benzonatate SE

Answer 19

CNS depression

Question 20

Dextromethorphan, Codeine
and Benzonatate nursing consideration

Answer 20

Potential for abuse

do not take w/ other CNS depressants

Question 21

what class is Guaifenesin (Mucinex)

Answer 21

expectorant

Question 22

expectorant MOA

Answer 22

Reduction in surface tension of secretion helping thin the mucus which makes it easier to expectorate

Question 23

Guaifenesin (Mucinex) indication

Answer 23

Decrease mucus in colds, bronchitis

Question 24

Guaifenesin (Mucinex) SE

Answer 24

Mild GI distress

Question 25

Guaifenesin (Mucinex) nursing consideration

Answer 25

**Encourage fluids** Be cautious w/ pts with chronic cough or asthma

Question 26

what class is Acetylcysteine

Answer 26

mucolytic

Question 27

mucolytic MOA

Answer 27

Decreases viscosity of mucus making it easier to cough

Question 28

Acetylcysteine indication

Answer 28

Bronchopulmonary disease, cystic fibrosis

Question 29

Acetylcysteine SE

Answer 29

Bronchospasm

Question 30

Acetylcysteine nursing consideration

Answer 30

Horrible smell **Monitor lung sounds** Neb treatment