Thyroid Dysfunction (405) Flashcards
goiter
enlarged thyroid gland caused by thyroiditis, benign thyroid nodules, malignancy, iodine deficiency
hyperthyroidism
inc T3&T4, dec TSH
most of the time caused by graves disease
hypothyroidism
dec T3&T4, inc TSH
hashimoto’s
toxic goiter
refers to goirt w/ hyperthyroidism
non toxic goiter
refers to goiter w/ normal thyroid levels
iodine can be found in what foods
yogurt, milk, eggs and iodized salt
hyperthyroidism S/s
-inc HR, murmurs, dysrhyth, palpitations, angina
-inc RR & DOE
-inc appetite & thirst
-weight loss
-inc peristalsis & diarrhea
-memory lapses / short attention span
hyperthyroidism physical sx
-warm, moist, smooth skin
-hair loss
-palmar erythema
-fine silky hair
-diaphoresis
-vitiligo
-exophthalmos
-bruit over thyroid gland
drug therapy for hyperthyroidism
-anti thyroid (tapazol)
-iodine therapy (SSKI & Lugols)
-beta blockers
-radioactive iodine therapy
acute thyrotoxicosis / crisis/ storm
-results from stressor (infection, trauma, surgery)
-pt having a thyroidectomy are at risk d/t manipulation of the hyperactive thyroid
-S/s: severe hyperthyroid sx
SSKI
-used to prepare pt for thyroidectomy
-inhibits synthesis of T3&4 and dec the vascularity of the thyroid gland
radioactive iodine therapy
-used for med mgt of hyperthyroidism
-treatment of choice for non pregnant adults
-take it PO (do not need to be admitted)
-radio iodine is rapidly incorporated into the thyroid & its beta emissions result in extensive local tissue damage (delayed response tho)
-give anti thyroid drugs & beta blockers for sx mgt
pt secretions will be radioactive for a few days & if thyroid is destroyed they need to supplement for life
radioactive iodine therapy precautions
minimize direct contact for 2-3 days, double flush toilet, separately launder clothes and use seperate towels
subtotal thyroidectomy
-removal of large portion (90%) of the thyroid gland
-hypo will occur if too much is taken
-indicated for those not responsive to anti thyroid therapy, large goiters or possibility of malignancy
less invasive surgical mgt of hyperthyroidism
endoscopic thyroidectomy
post op interventions for subtotal thyroidectomy
-assess for hemorrhage or tracheal compression
-hoarseness will be expected for 3-4 days post surgery
-semi fowlers w/ head on pillow, avoid flexion or any tension on suture line
-monitor vitals & Ca levels
serum calcium concerns w/ thyroid removal
-tetany secondary to (accidental) hypoparathyroidism
-S/s: tingling in toes/fingers/around mouth muscular twitching & apprehension
-monitor for trousseau’s & chvostek’s sign
hypothyroidism S/s
wt gain, depression, fatigue, slow mentation, slow speech, somnolence, low exercise tolerance,
DOE, anemia, constipation, cold intol, hair loss, dry skin, goiter, difficulty swallowing & myxedema
myxedema
changes seen in the skin and tissue d/t prolonged hypothyroidism -> swelling is hard & non pitting
can be reserved w/ thyroid replacement
myxedema coma
-severe hypothyroidism w/ very low thyroid hormone levels
-a medical emergency
-IV thyroid hormones & steroids given
-mental status changes / unresponsive
myxedema coma causes
HF, stroke, infections, not taking thyroid meds
med mgt of hypothyroidism
-thyroid hormone replacement (levothyroxine)
-monitor TH levels & adjust dosage prn
-nutrition for wt loss
T3&T4 w/ hypothyroidism
low
TSH w/ hypothyroidism
high when defect is the thyroid
low when iti is in the pituitary or hypothalamus