endocrine labs & dx (405) Flashcards
the master gland is
the pituitary gland
the anterior pituitary gland secretes
TSH & ACTH
the posterior pituitary gland secretes
ADH & oxytocin
the hypothalamus secretes
CRF
ADH is the regulator of
pure water
no electrolytes will be found within this water
ADH regulation
inc plasma osmolality -> ADH release from posterior pituitary -> reabsorption of H2O in kidney tubules -> inc plasma volume & dec plasma osmolality -> ADH inhibited by normal osmolality
parathyroid regulates
calcium and phosphorous
the thyroid is regulated by
TSH
the thyroid secretes
T4, T3 and calcitonin
water deprivation test
-used to differentiate causes of DI (neurogenic or nephrogenic vs psychogenic polydipsia)
-ADH is administered and we monitor output/specific gravity & serum osmolality every hour or 2hrs during the test
aldosterone regulates and what does this regulation cause
Na+
inc Aldosterone -> inc Na+ retention, inc water retention & inc BP
when assess hyperaldosteronism, what must the pt do
maintain assigned position for 2 hours (supine vs upright)
cortisol assessment evaluates
status of adrenal cortex function
take 24 urine cortisol
what is serum cortisol affect by
diurnal variation & stress
ex: cortisol will be higher in the AM
ACTH testing evaluates
adrenal function
what is the most sensitive test used to evaluate thyroid dysfunction
blood TSH
T3&T4 can be used to evaluate
thyroid function and monitoring thyroid therapy
thyroid scan
-used to evaluate nodules
-radioactive isotopes given PO or IV
-warm spot = benign nodules
-cold spot = malignant tumors
-encourage fluids after
if a malignant tumor is found during a thyroid scan, what is the next step
tumor biopsy to confirm diagnosis
radioactive iodine uptake
-provides direct measure of thyroid activity
-evaluates function of nodules
-radioactive iodine given PO or IV
-uptake measured at several intervals for 24hrs
-values expressed in %
normal FBG & CBG
<126 ; <200
A1c
normal: 4-6%
preDM: 6.1-6.4%
DM: 6.5% or greater
DM target: 7%
high ketones are associated w/
hyperglycemia
what ketone level is considered a medical emergency (DKA)
> 300