Unit 8: Blood / Lymphatic / Cardiovascular Systems Flashcards
are the red blood cells or RBC’s. responsible for transporting oxygen and carbon dioxide
erythrocytes
are the white blood cells of WBC’s. responsible for protecting the body against infection
leukocytes
are platelets or plts. they assist in hemostasis and blood clotting
thrombocytes
is the fluid portion of blood
plasma
what are the three formed elements of blood
erythrocytes
leukocytes
thrombocytes
how many red blood cells are there per cubic millimeter
4.8-5.4 million
where are red blood cells produced
red bone marrow
why are red blood cells a biconcave disk
so the cell can move without injury through the narrow blood capillaries
highest level of surface area to carry oxygen
is the principle pigment of the erythrocyte
hemoglobin
one hemoglobin is composed of how many protein chains called globin
4
each protein chain contains a reg pigment called
heme
what part of the hemoglobin transports O2
heme
what part of the hemoglobin transports CO2
globin
what are the five leukocytes
neutrophils basophils eosinophils lymphocytes monocytes
have cytoplasmic granules which stain pink or light purple. most numerous of all leukocytes.
neutrophils
have large cytoplasmic granules which stain dark blue or purple.
basophils
contain large cytoplasmic granules which stain reddish-orange
eosinophils
what are the three granular leukocytes
neutrophils
basophils
eosinophils
have a dark kidney shaped nucleus. light bluish=gray cytoplasm. become macrophages
monocytes
have a large spherical nucleus surrounded by a limited amount of pale blue stained cytoplasm. will specialize into T, B, lymphocytes
Lymphocytes
are the leukocytes that perform phagocytosis
Monocytes, neutrophils
are present in bacterial infection
neutrophils
cells produce histamine (inflammation response) and heparin (anticoagulant)
Basophils
ingest inflammatory chemicals and proteins to help protect against allergens (allergies)
eosinphils
are the largest of the leukocytes
Monocytes
are the smallest of the leukocytes
Lymphocytes
what are the agranular leukocytes
monocytes
leukocytes
refers to stopping blood flow which is extremely important when the blood vessels are damaged. (blood clotting)
hemostasis
what are the three stages of hemostasis
vascular spasm, platelet plug formation, and coagulation
occurs when an arteriole or venule is broken or has been cut. muscles in the blood vessel wall are stimulated to contract and the blood loss is decreased almost immediately
vascular spasm
platelets tend to stick to the exposed ends (collagen) or injured blood vessels.
platelet plug formation
is the actual formation of a clot;
coagulation
is a blood clot that has formed abnormally in a blood vessel. a STATIONARY blood clot
thrombus
occurs when a thrombus has been dislodged or fragmented and is carried away from the original site by the flow of blood. MOVING blood clot
embolus
what are the four blood types
A, B, AB, O
blood type A has what antigen and what antibody
antigen A, Antibody B
bloody type B has what antigen and what antibody
antigen B, Antibody A
blood type AB has what antigen and what antibody
antigens A and B, Neither antibody
blood type O has what antigen and what antibody
Neither, Both antibodies A and B
refers to the presence or absence protein D on the membranes of the erythrocytes
Rh factor
refers to the presence of protein D on the erythrocyte membrane
Rh+
refers to the absence of protein D on the erythrocyte membrane
Rh-
results from inadequate numbers of erythrocytes or a deficiency in the production of normal hemoglobin
anemias
is caused by a decrease in the amount of circulating erythrocytes lost because of hemorrhage or bleeding. associated with trauma or surgery
hemorrhagic anemia
is characterized by the inability of the red bone marrow to produce erythrocytes which have been destroyed due to toxic chemicals; associated with chemotherapy patients
aplastic anemia
occurs when the body is deficient of iron which impairs the body’s ability to make normal hemoglobin
iron deficiency anemia
occurs when there is a dietary deficiency of vitamin B12 or the loss of the intrinsic factor from the lining of the stomach which prevents B12 absorption
pernicious anemia
results from the abnormal destruction of erythrocytes.
hemolytic anemia
occurs in the fetus if the fetus is Rh+ while the mother is Rh-. the antibodies cross the placena and begin to destroy the Rh+ red blood cells
hemolytic disease of the Newborn OR erythroblastosis fetalis
results in the inability to produce blood-clotting factor VIII. fibrinogen cannot be converted to fibrin and the blood cannot clot
hemophilia
is a cancer of the blood characterized by the overproduction of immature white blood cells
leukemia
is a noncancerous leukocyte disorder caused by a virus. transmitted in the saliva and is nicknamed the “kissing disease”
mononucleosis or infectious mononucleosis
is an excessive number of erythrocytes. disease is caused by an overproduction of blood cells within the body
polycythemia
is an deficiency in white blood cells in the body
leukocytopenia
LYMPHATIC SYSTEM
…
are large lymphoid nodules located in the wall of the pharynx, and include the adenoids and palatine
tonsils
is the largest collection of lymphatic tissue in the body; located in the LUQ
spleen
is posterior to the sternum and superior to the heart; produces a hormone called thymosin which helps to mature lymphocytes into T-lymphocytes (T-cells)
thymus
are small, oval, lymphatic organs which are surrounded by a fibrous capsule. located in clusters along the lymphatic vessels. contain large number of lymphocytes.; filter and purify the lymph before it is returned to the blood
lymph nodes
production of all blood cell types; located in the spongy bone
red bone marrow
are similar to veins containing valves. transport lymph through the body back to the blood
lymph vessels
is a foreign protein capable of initiating the immune response and the production of antibodies
antigen
is a globular protein produced by the B-plasma cells which will bind to specific antigens to promote their destruction or removal
antibodies
are white blood cells which were produced in the bone marrow and mature in the thymus gland
T-cells
CMI
cell-mediated immunity
what are the four T-cells
Cytotoxic (NK) T-cells
Helper T-cells
Memory T-cells
Suppressor T-cells
are known as the killer T-cells which help to tract down bacteria, fungi, or foreign tissues that contain antigens. perform phagocytosis
Cytotoxic T-cells
release a variety of chemicals which help to coordinate specific and nonspecific defenses, stimulate cell-mediated immunity
Helper T-cells