Unit 5: cell Signaling Flashcards
what are the signals
ligands- chemical/molecule binds to receptor
how are signals received?
ligand binds the receptor
what happens to a receptor when it binds to a ligand (signal)? *gum ball analogy
receptor changes shape (conformational shift )
how do cells communicate?
send electrical or chemical signals
3 stages of cell signaling
- reception
- transduction
- response
in cell signaling, what does reception do
receive signal
ligand bind to receptor
what does transduction do?
bind molecule and relay info to inside of cell
translate signal from where it received it into being able to be read from the inside
what does response do?
cell decision, actions due to signal
what is it, how does it look, how close is the range, and what kind of cells receive it? where is it used
Gap junction
direction connection of 2 cell cytoplasm
very short range
very specific
heart and brain
what is it, how does it look, how close is the range, and what kind of cells receive it? cell to cell contact
direct contact of 2 cells
very short range and very specific
what is it, how does it look, how close is the range, and what kind of cells receive it? where is it used
synaptic transmission
neuron releasing signal onto another cell
short/ long range
specific
nervous system
what is it, how does it look, how close is the range, and what kind of cells receive it? where is it used
paracrine
signaling to nearby cells
medium range
general
tissue damage
what is it, how does it look, how close is the range, and what kind of cells receive it? where is it used
endocrine
signaling to cell far away using the blood stream
long range
general
how to receptors work? 3 key characteristics
bind to ligand(signal)
use weak bonds
specific
dynamic (moving, constant on and off )
how can you compare the strength of ligand binding to receptor?
KD
