Unit 4 - Blood System Flashcards

1
Q

Function of blood

A

transport system for maintaining a constant environment for living tissues throughout body

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2
Q

Blood volume contains what 5 components?

A
  1. plasma (liquid)
  2. erythrocytes (RBC)
  3. leukocytes (WBC)
  4. platelets / thrombocytes
  5. serum
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3
Q

erythrocytes

A
  • RBC
  • contain hemoglobin to carry O2
  • formed in bone marrow
  • live 120 days
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4
Q

leukocytes

A

Granulocytes - 3 kinds - most numerous

Agranulocytes - 2 kinds

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5
Q

Basophils

A
granulocyte
contain heparin (anticlotting) & histamine (released in allergic response
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6
Q

Eosinophils

A

granulocytes
increase in allergic responses
engulf substances that trigger allergies

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7
Q

neutrophils

A

granulocyte

  • phagocytes that accumulate at sites of infection
  • ingest & destroy bacteria
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8
Q

monocyte

A

agranulocyte
mononuclear
- get ride of cellular debris
- phagocytic that fight disease

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9
Q

lymphocyte

A

agranulocyte

  • made in bone marrow & lymph nodes
  • make antibodies
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10
Q

platelets

A

also: thrombocytes

blood cell fragments that help with clotting

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11
Q

erythropoietin

A

hormone secreted by kidneys that stimulates production of RBC in bone marrow

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12
Q

plasma

A

liquid portion of blood that contains:

  • water
  • dissolved proteins
  • sugar
  • wastes
  • salts
  • hormones
  • and other substances
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13
Q

4 types of plasma proteins

A
  1. albumin
  2. globulin
  3. fibrinogen
  4. prothrombin
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14
Q

albumin

A

maintains proper concentration of water in blood

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15
Q

globulin

A

immunoglobins - antibodies that bind to and destroy antigens

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16
Q

fibrinogen

A

clotting protein

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17
Q

prothrombin

A

clotting protein

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18
Q

serum

A
  • plasma minus clotting protein & cells

- clear, yellowish fluid that separates from blood when it clots

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19
Q

pancytopenia

A

deficiency of all 3 components (RBC, WBC, and platelets)

20
Q

-cytosis

A

abnormal condition of cells

macrocytosis - condition of big cells

21
Q

chrom/o

A

color

hypochromia - low concentration of hemoglobin in RBC

22
Q

morph/o

A

shape

morphology - study of shapes, form

23
Q

poikil/o

A

irregular; varied

poikilocytosis - irregularity in shape of RBC

24
Q

spher/o

A

globe; round
spherocytosis - auto-hemolytic anemia (a disease of the blood) characterized by the production of RBCs that are sphere-shaped, rather than bi-concave disk shaped

25
blood dyscrasia
very broad term meaning any abnormal or pathologic condition of the blood
26
anemia
deficiency in erythrocytes or hemoglobin
27
aplastic anemia
failure of good cell production in bone marrow
28
pernicious anemia
lack of RBC due to inability to absorb vitamin B12
29
sickle cell anemia
hereditary; abnormal shape of RBC leads to inability to carry hemoglobin sickle-shaped
30
hemolytic anemia
reduction in RBC due to excessive destruction
31
purpura
multiple pinpoint hemorrhages and accumulation of blood under skin deficiency of platelets - thrombocytopenia autoimmune
32
leukemia
"blood condition of white" - disease of bone marrow where malignant leukocytes fill marrow and bloodstream - classification due to which leukocyte is involved
33
thrombocytopenia
- deficiency of platelets in blood | - low production or increased destruction
34
PTT
Partial Thromoplastin Time - platelet count - test done when someone is on a blood thinner - measures presence of factors involved in clotting
35
PT
Prothrombin time - test of the ability of blood to clot - test done when someone is on a blood thinner - measures presence of factors involved in clotting
36
hematocrit
Hct | % of RBC in volume of blood
37
bleeding time
time required for blood to stop flowing from a tiny puncture wound - normal = 8 min
38
coagulation time
time for venous blood to clot in a test tube | normal =
39
type A blood 1. can receive: 2. cannot receive
1. A, O | 2. B, AB
40
Type B blood 1. can receive: 2. cannot receive
1. B, O | 2. A, AB
41
Type AB blood 1. can receive: 2. cannot receive
1. AB, O, A, B | 2. none
42
Type O blood 1. can receive: 2. cannot receive
1. O | 2, A, B, AB
43
Rhesus factor
``` + = have it (can get both + and -) - = don't have it (can only get -) ```
44
where does hemoglobin go to get broken down?
spleen liver bone marrow
45
condition of bilirubin in urine?
bilirubinuria
46
BMT
bone marrow transplant
47
3 major ways for jaundice to occur:
1. excessive destruction of RBC (hemolysis) 2. blocked bile duct 3. damaged liver