U1 Lecture 5 Flashcards
Describe the principal characteristics/ functions of the following list of cellular structures: 1. Cytoskeleton (microtubules and microfilaments) 2. Mitochondria 3. Nucleus 4. smooth and rough endoplasmic reticulum 5. golgi apparatus 6. lysosomes and peroxisomes - Compare and contrast the characteristics of ATP production by oxidative vs. anaerobic metabolism
Two categories of organelles
- Membranous
2. Non-membranous
Types of membranous organelles
- Mitochondria
- Endoplasmic Reticulum (ER)
- Golgi complex
- (Nucleus)
Types of non-membranous organelles
- Cytoskeleton
- Ribosomes
- Proteasomes
Cytoskeleton characteristics
- Microfilaments - strands of protein (actin)
- Intermediate filaments - keratins
- Microtubules - strands of tubulin
Cytoskeleton functions
Microfilaments -
- connect organelles to membranes
- Influence cell motility and shape
Intermediate filaments - structural stability
Mictrotubules
- Influence cell structure and shape
- Motility (organelle movement and cillia/flagella)
Mitochondria
The major site of cell energy metabolism
Oxidative ATP Production
Energy metabolism occurs in…
- Cytoplasm- through glycolysis
- Mitochondria- through oxidative phosphorylation
Oxidative Phosphorylation
Enzymatically- controlled ‘breaking of bonds’
- Consumes O2
- Produces CO2
- Efficient production of ATP
Glycolysis
- 1st step in breakdown of glucose to extract energy for cellular metabolism
- Takes in ADP energy and Psubi and releases ATP to make pyruvate (a salt of pyruvic acid)
Endoplasmic Reticulum (ER) functions
- Lipid & protein synthesis
- Storage (protein; Ca2+)
- Transport within the cell
- Detoxification
Two types of endoplasmic reticulum and their functions
- Rough ER - protein synthesis and storage
2. Smooth ER - Lipid synthesis and Ca2+ storage
Golgi Apparatus functions
Site of packaging and processing of protein products for secretion
- transport vesicles from rough ER enter golgi and leave through exoytosis
Lysosomes function
Contain digestive enzymes for recycling old cellular material etc.
Peroxisomes
Contain enzymes for detoxification of byproducts of metabolism