type 1 diabetes (own work) Flashcards
1
Q
what is type 1 diabetes mellitus?
A
-Autoimmune disease that causes destruction of pancreatic beta cells resulting in beta cell deficiency and high blood glucose
2
Q
what are the signs/symptoms of T1DM?
A
- weight loss
- polyuria
- ketonuria +/- metabolic acidosis
- fatigue
- thirst
3
Q
what investigations would you do for someone with suspected type 1 diabetes?
A
- fasting glucose x2
- random glucose test
- antibody test
- HbA1c
4
Q
what antibodies are associated with T1DM?
A
- anti GAD
- anti islet cell antibodies
5
Q
what are complications of type 1 diabetes mellitus?
A
-diabetic ketoacidosis
macrovascular complications= heart disease and stroke
microvascular complications= retinopathy, neuropathy and nephropathy
6
Q
what level is HbA1c in a type 1 diabetic?
A
<70 HbA1c= 48
>70 HbA1c= 53
7
Q
what level is fasting glucose in a diabetic?
A
7 or > mmol/L