treatment for type 2 diabetes

Question 1

what are the aims for management for type 2 diabetes?

Answer 1

• treat symptoms
• prevent microvascular complications
• prevent cardiovascular complications
• screen for complications early while treatable

Question 2

what is the major contributor for patients getting type 2 diabetes?

Answer 2

obesity

Question 3

can type 2 diabetes be reversed?

Answer 3

if caught early and patient adopts healthier lifestyle/loses weight then their diabetes can go into remission

Question 4

what HbA1c are you aiming for?

Answer 4

targets should be set with individuals in order to balance benefits with harm.

Usually <7% (53mmol/mol)

• an HbA1c of 7.0% (53mmol/mol) among people with type 2 diabetes is reasonable to reduce the risk of microvascular and macrovascular disease
• a target of 6.5% (48mmol/mol) may be appropriate at diagnosis

Question 5

for a patient on triple therapy or insulin what should their HbA1c target be?

Answer 5

more relaxed

58mmol/mol may be appropriate

Question 6

what are insulin secretagogues?

Answer 6

drugs that work on the pancreatic beta cell to make the beta cell produce more insulin

Question 7

what are insulin sensitizers?

Answer 7

-drugs that make the insulin work better

Question 8

what are examples of insulin secretagogues?

Answer 8

• sulphonyluraes
• DPP4 inhibitors
• GLP-1RA

Question 9

what are some examples of insulin sensitizers?

Answer 9

• metformin

- thiazolidinediones