Two Week Wait Flashcards

1
Q

TWW testicular ca indications (3 things)

A

solid intratesticular lump, non-painful enlargement/change in shape of testis, abnormal testicular US

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2
Q

TWW prostate ca indications (2 things)

A

feels malignant on DRE, PSA >age-related NR

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3
Q

TWW bladder ca indications (3 things)

A

> 45 y.o. + visible haematuia (persistent/recurrus after UTI Rx), >45 y.o. + unexplained visible haematuria w/o urinary symptoms, >60 y.o. + unexplained non-visible haematuria + dysuria/high WCC

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4
Q

TWW renal ca indications (3 things)

A

abnormal US suggestive of ca, >45 y.o. + visible haematuia (persistent/recurrus after UTI Rx), >45 y.o. + unexplained visible haematuria w/o urinary symptoms

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5
Q

TWW penile ca indications (3 things)

A

penile mass/ulcerated lesion (STI excluded), persistent penile lesion post-STI Rx, unexplained/persistent glans/foreskin symptoms

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6
Q

at what age to worry about visible haematuria

A

45

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7
Q

at what age to worry about non-visible haematuria

A

60

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8
Q

causes to rule out in visible/non-visible haematuria

A

UTI, stones, trauma, GN

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9
Q

TWW brain/CNS ca indications (9 things)

A

suspicious MRI/CT, new onset seizures (focal/interictal focal deficit), progressive sub-acute loss of central neuro funciton, unexplained rapid personality/behavioural/slowness/cognitive change, headache + sinister features suggestive of raised ICP, isolated new onset daily headache <12/52 duration, CN palsy, visulal changes, Hx of ca + neuro symptoms

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10
Q

f and duration of new onset headache to be suspicious

A

daily, <12/52

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11
Q

ASAP referral for retinoblastoma (1 thing)

A

absent red reflex in children

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12
Q

TWW for intraocular tumour (3 things)

A

unexplained vision loss, ux proptosis/globe displacement, CT/MRI suspicious

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13
Q

TWW ovarian ca indications (4 things)

A

suspicious abdo/pelvic US, ascites, pelvic/abdo mass, CA125 >35

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14
Q

TWW endometrial ca indications (2 things)

A

suspicious abdo/pelvic US, PMB (>12/12 post-last bleed)

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15
Q

TWW cervical ca indication (1 thing)

A

suspicious cervix appearance

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16
Q

TWW vaginal ca indication (1 thing)

A

unexplained palapble mass in/at entrance to vagina

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17
Q

TWW vulval ca indications (3 things)

A

unexplained lump, unexplained ulceration, unexplained bleeding

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18
Q

worry RE CA125 >

A

35

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19
Q

how long after menopause os PMB considered

A

12/12

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20
Q

TWW leukaemia indications (5 things)

A

abnormal FBC/blood film consistent with leukaemia, unexplained/persistent/recurrent infections, unexplained bruising, unexplained bleeding, unexplained petechiae

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21
Q

TWW myeloma indications (5 things)

A

protein electrophoresis suggestive of myeloma, urine BJ protein, > 40 y.o. + unexplained #, >40 y.o. + >6/52 bone pain, >40 y.o. + back pain + red flag

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22
Q

TWW lymphona indications (8 things)

A

unexplained lymphadenopathy, persistent lymphadenopathy > 6/52 >2cm, unexplained splenomegaly, fever, night sweats, SOB, pruitis, weight loss

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23
Q

leukaemia FBC

A

pancytopenia, anaemia, neutropaenia, thrombocytopaenia, may just be anaemia in the chronic cases

24
Q

leukaemia blood film

A

blasts

25
Q

unexplained bruising/bleeding/petechiae are suggestive of

A

leukaemia

26
Q

protein found in the urine indicative of myeloma

A

Bence Jones

27
Q

worry RE unexplained # >

A

40

28
Q

duration + age > which we worry about bone pain

A

6/52, >40

29
Q

back pain + red flag worry >

A

40

30
Q

persistent lymphadenopathy duration + size

A

6/52, >2cm

31
Q

TWW laryngeal/pharyngeal ca indications (6 things)

A

unexplained neck/throat lump/mass, >40 y.o. + horseness (>3/52), >4/52 persistent ux pain/discomfort in throat, >40 y.o. + dysphagia >3/52, >40 y.o. + odynophagia (3/52), >40 y.o. + otalgia (3/52)

32
Q

TWW ear/nose/sinus ca indications (6 things)

A

persistent ux otalgia, serosanguinous nasal discharge >4/52, ux nasal obstruciton + purulent discharge, facial/CN palsy/neuropathy, orbital mass, severe facial pain

33
Q

TWW thyroid ca indications (2 things)

A

unexplained solitary thyroid lump, suspicious US

34
Q

TWW oral/lip ca indications (5 things)

A

> 3/52 unexplained oral ulceration, suspicious lump/mass on lip/in oral cavity, red/red + white patch in oral cavity (leukoplakia/erythroleukoplakia), tooth mobility w/o periodontal DZ, poor healing >3/52 post-tooth extraction

35
Q

TWW salivary ca indications (2 things)

A

> 40 y.o. + unexplained/persistent parotid/submandibular swelling, firm submucosal swelling in oral cavity

36
Q

worry about horseness/dysphagia/odynophagia/otalgia age + duration

A

> 40 y.o., >3/52

37
Q

worry about persistent us discomfort/pain in throat

A

> 4/52

38
Q

TWW power GI ca indications (9 things)

A

suspicious investigation (colonoscopy/flexisig), suspicious abdo/recctal mass, unexplained anal mass/ulceration, >40 y.o. + unexplained abdo pain + weight loss, >40 y.o. + unexplained Fe- anaemia, <50 y.o. + PR bleeding + abdo pain/change in bowel habits/weight loss/Fe- anaemia, >50 y.o. + unexplained PR bleeding, >50 y.o. + unexplained change in bowel habits, >60 y.o. + unexplained anaemia

39
Q

worry RE abdo pain + weight loss >

A

40

40
Q

worry RE unexplained Fe- anaemia >

A

40

41
Q

worry RE PR bleeding + abdo pain/change in bowel habits/weight loss/Fe- anaemia

A

50

42
Q

worry RE PR bleeding >

A

50

43
Q

worry RE unexplained change in bowel habits >

A

50

44
Q

worry RE unexplained anaemia >

A

60

45
Q

TWW L ca indications (4 things)

A

suspicious CXR/CT, >40 y.o. + unexplained haemoptysis, >40 y.o. + unexplained finger clubbing/unexplained thrombocytosis/unexplained cervical/supraclavicular lymphadenopathy/unexplained chest signs/unexplained perssistent/recurrent chest infections, features of metastatic DZ

46
Q

worry RE haemoptysis >

A

40

47
Q

2WW melanoma indications (7 things)

A

major criteria: change in size, irregular shape, irregular colour
minor criteria: largest diameter >7mm, oozing, inflammation, change in sensation

48
Q

2WW 1’ bone sarcoma indications (3 things)

A

suspicious XR, bone swelling/tenderness, bone pain not responding to simple analgesia

49
Q

worry when mole diameter >

A

7mm

50
Q

2WW oesophagus/stomach ca indicaitons (2 things)

A

suspicious endoscopy, upper abdo mass

51
Q

2WW pancreas ca indications (2 things)

A

suspicious abdo CT/US, >40 y.o. + jaundice

52
Q

2WW liver/GB ca indication (1 thing)

A

suspicious US

53
Q

worry RE jaundice in >

A

40s

54
Q

2WW breast ca indications (6 things)

A

breast lump, persistent/unexplained axilliary lump, ux nipple discharge (blood stained/serous)/retraction/ulceration/distortion/eczema resistent to topical steroids, skin changes (nodules, ulceration, peau d’orange, dimpling), ux non-cyclical breast pain, men > 50 y.o. + subareolar lump

55
Q

worry RE breast lumps in men >

A

50