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Medicine > Dermatology > Flashcards

Dermatology Flashcards

1
Q

shin lesion DD

A

erythema nodosum, pretibial myxoedema, pyoderma gangrenosum, necrobiosis lipoidica diabeticorum

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2
Q

erythema nodosum features

A

symmetrical, erythematous, tender, nodules that heal w/o scarring

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3
Q

most common causes of erythema nodosum

A

strep, sarcoidosis, IBD, iatrogenic (penicillins, sulphonamides, OCP)

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4
Q

pretibial myxoedema features

A

symmetrical, erythematous lesions, shiny, orange peel skin

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5
Q

pretibial myxoedema is seen in

A

Grave’s DZ

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6
Q

pyoderma gangrenosum

A

initially: small red papule, later: deep, red, necrotic ulcer, violaceous border

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7
Q

most common causes of pyoderma gangrenosum

A

idiopathic

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8
Q

pyoderma gangrenosum is associated with

A

IBD, CT DZ, myeloproliferative disorders

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9
Q

necrobiosis lipoidica diabeticorum

A

shiny, painless, yellow/red skin, shins, DM

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10
Q

necrobiosis lipoidica diabeticorum often associated with

A

telangectasia

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11
Q

symmetrical, erythematous, tender, nodules that heal w/o scarring are features of

A

erythema nodosum

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12
Q

strep, sarcoidosis, IBD, iatrogenic (penicillins, sulphonamides, OCP) are causes of

A

erythema nodosum

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13
Q

symmetrical, erythematous lesions, shiny, orange peel skin are features of

A

pretibial myxoedema

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14
Q

Skin manifestation of Grave’s DZ

A

pretibial myxoedema

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15
Q

initially: small red papule, later: deep, red, necrotic ulcer, violaceous border are features of

A

pyoderma gangrenosum

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16
Q

shiny, painless, yellow/red skin, shins, DM are features of

A

necrobiosis lipoidica diabeticorum

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17
Q

types of hypersensitivity reaction

A

I = anaphylactic, II = cell bound, III = immune complex, IV = delayed hypersensitivity

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18
Q

type I hypersensitivity reaction examples

A

anaphylaxis, atopy (eczema, asthma, hay fever)

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19
Q

type II hypersensitivity reaction examples

A

AI haemolytic anaemia, ITP, Goodpasture’s S, pernicious anaemia, acute haemolytic transfusion reactions, rheumatic fever, pemphigus vulgaris/bullous pemphigoid

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20
Q

type III hypersensitivity reaction examples

A

serum sickness, SLE, PSGN, extrinsic allergic alveolitis (especially acute phase)

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21
Q

type IV hypersensitivity reaction examples

A

TB, tuberculin skin reaction, GVHD, allergic contact dermatitis, scabies, extrinsic allergiv alveolitis (esp chronic phase), MS, GBS

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22
Q

type V hypersensitivity reaction examples

A

Graves’, MG

23
Q

anaphylaxis, atopy (eczema, asthma, hay fever) are examples of

A

type I hypersensitivity reaction

24
Q

AI haemolytic anaemia, ITP, Goodpasture’s S, pernicious anaemia, acute haemolytic transfusion reactions, rheumatic fever, pemphigus vulgaris/bullous pemphigoid are examples of

A

type II hypersensitivity reactions

25
Q

serum sickness, SLE, PSGN, extrinsic allergic alveolitis (especially acute phase) are examples of

A

type III hypersensitivity reaction

26
Q

TB, tuberculin skin reaction, GVHD, allergic contact dermatitis, scabies, extrinsic allergiv alveolitis (esp chronic phase), MS, GBS are examples of

A

type IV hypersensitivity reaction

27
Q

Graves’, MG are examples of

A

type V hypersensitivity reaction

28
Q

eczema herpeticum management

A

admission, IV acyclovir (potentially life threatening)

29
Q

lichen planus features

A

itchy, papular, palms, soles, genitalia, flexor surfaces, white lace pattern (Wickham’s striae), Koebner phenomenon, oral involvement, thinning of nail plate, longitudinal ridges

30
Q

causes of lichenoid drug eruptions

A

gold, quinine, thiazides

31
Q

management of lichen planus

A

topical steroids, PO steroids/immunosuppression if extensive

32
Q

itchy, papular, palms, soles, genitalia, flexor surfaces, Wickham’s striae, Koebner phenomenon, oral involvement, thinning of nail plate, longitudinal ridges are features of

A

lichen planus

33
Q

gold, quinine, thiazides can cause

A

lichenoid drug erruption

34
Q

mycosis fungoides is

A

a rare form of T-cell lymphoma that affects the skin

35
Q

mycosis fungoides features

A

itchy, red patches, differing colours

36
Q

mycosis fungoides is easily confused with

A

eczema/psoriasis

37
Q

a rare form of T-cell lymphoma that affects the skin

A

mycosis fungoides

38
Q

itchy, red patches, differing colours, easily confused with eczema/psoriasis

A

mycosis fungoides

39
Q

exacerbating factors for psoriasis

A

trauma, alcohol, drugs (B-blockers, Li, antimalarials (chloroquine, hydroxychloroquine), NSAIDs, ACEi, infliximab), withdrawal of systemicsteroids

40
Q

guttate psoriasis may be triggered by

A

strep infection

41
Q

acanthosis nigricans features

A

symmetrical, brown, velvety plaques, neck, axilla, groin

42
Q

causes of acanthosis nigricans

A

GI ca, DM, obesity, PCOS, acromegaly, Cushing’s DZ, hypothyroidism, FH, Prada-Willi S, OCP, nicotinic acid

43
Q

symmetrical, brown, velvety plaques, neck, axilla, groin are features of

A

acanthosis nigricans

44
Q

GI ca, DM, obesity, PCOS, acromegaly, Cushing’s DZ, hypothyroidism, FH, Prada-Willi S, OCP, nicotinic acid may be causes of

A

acanthosis nigricans

45
Q

pemphigus vulgaris is

A

an AI DZ, common in the Ashkenazi Jewish populaiton

46
Q

pemphigus vulgaris features

A

mucosal ulceration, skin blistering, flaccid, easy rupturing, vesicles, bullae, Nikolsky’s sign

47
Q

management of pemphigus vulgaris

A

steroids, immunosuppression

48
Q

an AI DZ, common in the Ashkenazi Jewish populaiton describes

A

pemphigus vulgaris

49
Q

mucosal ulceration, skin blistering, flaccid, easy rupturing, vesicles, bullae, Nikolsky’s sign are features of

A

pemphigus vulgaris

50
Q

erythema multiforme features

A

target lesions, backs of hands/feet, spreads to torso, upper limbs > lower limbs, mild pruitis

51
Q

causes of erythema multiforme

A

HSV, idiopathic, mycoplasma, strep, drugs (penicillin, sulphonamides, carbamazepine, allopurinol, NSAIDs, OCP, nevirapine), SLE, sarcoidosis, ca

52
Q

erythema multiforme major vs minor

A

major involves the mucous membranes

53
Q

target lesions, backs of hands/feet, spreads to torso, upper limbs > lower limbs, mild pruitis are features of

A

erythema multiforme

54
Q

HSV, idiopathic, mycoplasma, strep, drugs (penicillin, sulphonamides, carbamazepine, allopurinol, NSAIDs, OCP, nevirapine), SLE, sarcoidosis, ca are causes of

A

erythema multiforme

Medicine (30 decks)

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