Dermatology

Question 1

shin lesion DD

Answer 1

erythema nodosum, pretibial myxoedema, pyoderma gangrenosum, necrobiosis lipoidica diabeticorum

Question 2

erythema nodosum features

Answer 2

symmetrical, erythematous, tender, nodules that heal w/o scarring

Question 3

most common causes of erythema nodosum

Answer 3

strep, sarcoidosis, IBD, iatrogenic (penicillins, sulphonamides, OCP)

Question 4

pretibial myxoedema features

Answer 4

symmetrical, erythematous lesions, shiny, orange peel skin

Question 5

pretibial myxoedema is seen in

Answer 5

Grave’s DZ

Question 6

pyoderma gangrenosum

Answer 6

initially: small red papule, later: deep, red, necrotic ulcer, violaceous border

Question 7

most common causes of pyoderma gangrenosum

Answer 7

idiopathic

Question 8

pyoderma gangrenosum is associated with

Answer 8

IBD, CT DZ, myeloproliferative disorders

Question 9

necrobiosis lipoidica diabeticorum

Answer 9

shiny, painless, yellow/red skin, shins, DM

Question 10

necrobiosis lipoidica diabeticorum often associated with

Answer 10

telangectasia

Question 11

symmetrical, erythematous, tender, nodules that heal w/o scarring are features of

Answer 11

erythema nodosum

Question 12

strep, sarcoidosis, IBD, iatrogenic (penicillins, sulphonamides, OCP) are causes of

Answer 12

erythema nodosum

Question 13

symmetrical, erythematous lesions, shiny, orange peel skin are features of

Answer 13

pretibial myxoedema

Question 14

Skin manifestation of Grave’s DZ

Answer 14

pretibial myxoedema

Question 15

initially: small red papule, later: deep, red, necrotic ulcer, violaceous border are features of

Answer 15

pyoderma gangrenosum

Question 16

shiny, painless, yellow/red skin, shins, DM are features of

Answer 16

necrobiosis lipoidica diabeticorum

Question 17

types of hypersensitivity reaction

Answer 17

I = anaphylactic, II = cell bound, III = immune complex, IV = delayed hypersensitivity

Question 18

type I hypersensitivity reaction examples

Answer 18

anaphylaxis, atopy (eczema, asthma, hay fever)

Question 19

type II hypersensitivity reaction examples

Answer 19

AI haemolytic anaemia, ITP, Goodpasture’s S, pernicious anaemia, acute haemolytic transfusion reactions, rheumatic fever, pemphigus vulgaris/bullous pemphigoid

Question 20

type III hypersensitivity reaction examples

Answer 20

serum sickness, SLE, PSGN, extrinsic allergic alveolitis (especially acute phase)

Question 21

type IV hypersensitivity reaction examples

Answer 21

TB, tuberculin skin reaction, GVHD, allergic contact dermatitis, scabies, extrinsic allergiv alveolitis (esp chronic phase), MS, GBS

Question 22

type V hypersensitivity reaction examples

Answer 22

Graves’, MG

Question 23

anaphylaxis, atopy (eczema, asthma, hay fever) are examples of

Answer 23

type I hypersensitivity reaction

Question 24

AI haemolytic anaemia, ITP, Goodpasture’s S, pernicious anaemia, acute haemolytic transfusion reactions, rheumatic fever, pemphigus vulgaris/bullous pemphigoid are examples of

Answer 24

type II hypersensitivity reactions

Question 25

serum sickness, SLE, PSGN, extrinsic allergic alveolitis (especially acute phase) are examples of

Answer 25

type III hypersensitivity reaction

Question 26

TB, tuberculin skin reaction, GVHD, allergic contact dermatitis, scabies, extrinsic allergiv alveolitis (esp chronic phase), MS, GBS are examples of

Answer 26

type IV hypersensitivity reaction

Question 27

Graves', MG are examples of

Answer 27

type V hypersensitivity reaction

Question 28

eczema herpeticum management

Answer 28

admission, IV acyclovir (potentially life threatening)

Question 29

lichen planus features

Answer 29

itchy, papular, palms, soles, genitalia, flexor surfaces, white lace pattern (Wickham's striae), Koebner phenomenon, oral involvement, thinning of nail plate, longitudinal ridges

Question 30

causes of lichenoid drug eruptions

Answer 30

gold, quinine, thiazides

Question 31

management of lichen planus

Answer 31

topical steroids, PO steroids/immunosuppression if extensive

Question 32

itchy, papular, palms, soles, genitalia, flexor surfaces, Wickham's striae, Koebner phenomenon, oral involvement, thinning of nail plate, longitudinal ridges are features of

Answer 32

lichen planus

Question 33

gold, quinine, thiazides can cause

Answer 33

lichenoid drug erruption

Question 34

mycosis fungoides is

Answer 34

a rare form of T-cell lymphoma that affects the skin

Question 35

mycosis fungoides features

Answer 35

itchy, red patches, differing colours

Question 36

mycosis fungoides is easily confused with

Answer 36

eczema/psoriasis

Question 37

a rare form of T-cell lymphoma that affects the skin

Answer 37

mycosis fungoides

Question 38

itchy, red patches, differing colours, easily confused with eczema/psoriasis

Answer 38

mycosis fungoides

Question 39

exacerbating factors for psoriasis

Answer 39

trauma, alcohol, drugs (B-blockers, Li, antimalarials (chloroquine, hydroxychloroquine), NSAIDs, ACEi, infliximab), withdrawal of systemicsteroids

Question 40

guttate psoriasis may be triggered by

Answer 40

strep infection

Question 41

acanthosis nigricans features

Answer 41

symmetrical, brown, velvety plaques, neck, axilla, groin

Question 42

causes of acanthosis nigricans

Answer 42

GI ca, DM, obesity, PCOS, acromegaly, Cushing's DZ, hypothyroidism, FH, Prada-Willi S, OCP, nicotinic acid

Question 43

symmetrical, brown, velvety plaques, neck, axilla, groin are features of

Answer 43

acanthosis nigricans

Question 44

GI ca, DM, obesity, PCOS, acromegaly, Cushing's DZ, hypothyroidism, FH, Prada-Willi S, OCP, nicotinic acid may be causes of

Answer 44

acanthosis nigricans

Question 45

pemphigus vulgaris is

Answer 45

an AI DZ, common in the Ashkenazi Jewish populaiton

Question 46

pemphigus vulgaris features

Answer 46

mucosal ulceration, skin blistering, flaccid, easy rupturing, vesicles, bullae, Nikolsky's sign

Question 47

management of pemphigus vulgaris

Answer 47

steroids, immunosuppression

Question 48

an AI DZ, common in the Ashkenazi Jewish populaiton describes

Answer 48

pemphigus vulgaris

Question 49

mucosal ulceration, skin blistering, flaccid, easy rupturing, vesicles, bullae, Nikolsky's sign are features of

Answer 49

pemphigus vulgaris

Question 50

erythema multiforme features

Answer 50

target lesions, backs of hands/feet, spreads to torso, upper limbs > lower limbs, mild pruitis

Question 51

causes of erythema multiforme

Answer 51

HSV, idiopathic, mycoplasma, strep, drugs (penicillin, sulphonamides, carbamazepine, allopurinol, NSAIDs, OCP, nevirapine), SLE, sarcoidosis, ca

Question 52

erythema multiforme major vs minor

Answer 52

major involves the mucous membranes

Question 53

target lesions, backs of hands/feet, spreads to torso, upper limbs > lower limbs, mild pruitis are features of

Answer 53

erythema multiforme

Question 54

HSV, idiopathic, mycoplasma, strep, drugs (penicillin, sulphonamides, carbamazepine, allopurinol, NSAIDs, OCP, nevirapine), SLE, sarcoidosis, ca are causes of

Answer 54

erythema multiforme