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Medicine > Pharmacology > Flashcards

Pharmacology Flashcards

1
Q

all severities of croup acute pharmacological management

A

PO dexamethasone 0.15mg/kg

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2
Q

sever croup additional pharmacological management

A

nebulised adrenaline 5mL 1:1000

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3
Q

examples of macrolides

A

M, Azithromycin, Clarithromycin, R, O, L, I, D, Erythromycin

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4
Q

pharmacological management of whooping cough

A

macrolide (azithromycin or clarithromycin)

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5
Q

anti-diarrhoeal agent

A

loperamide

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6
Q

zopiclone in elderly increases risk of

A

falls

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7
Q

zopiclone is used for

A

insomnia

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8
Q

clindamycin treatment is associated with a high risk of

A

C. diff - diarrhoea

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9
Q

bisphosphonates uses

A

prevention/Rx of osteoporosis, hypercalcaemia, Paget’s DZ, bone met pain

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10
Q

bisphosphonates SE

A

oesophagitis, oesophageal ulcers, osteonecrosis of the jaw, atypical stress #, fever, myalgia, arthralgia

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11
Q

how to take bisphosphonates

A

empty stomach, swallow whole, full glass of water, upright + NBM for 30’

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12
Q

bisphosphonate examples

A

alendronate

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13
Q

digoxin is used for

A

rate control AF

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14
Q

features of digoxin toxicity

A

lethargy, N, V, anorexia, confusion, yellow-green vision, arrhythmias, gynaecomastia

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15
Q

ABx CI in pregnancy

A

tetracyclines, aminoglycosides, sulphonamides, trimethoprim, quinolones

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16
Q

other drugs to avoid in pregnancy

A

ACEi, AGIIR antagonists, statins, warfarin, sulphonylureas, retinoids, cytotoxic agents, NSAIDs

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17
Q

SE of flucloxacillin

A

cholestasis (several weeks afterwards)

18
Q

SE of erythromycin

A

GI upset, prolonged QT, cholestasis

19
Q

SE of ciprofloxacin

A

reduced seizure threashold, tendonitis

20
Q

SE amoxacillin

A

rash with infectious mononucleosis

21
Q

SE co-amoxiclav

A

cholestasis

22
Q

SE metronidazole

A

reaction following EtOH ingestion

23
Q

SE doxycyclizine

A

photosensitivity

24
Q

SE trimethoprim

A

rashes (inc photosensitivity), pruitis, suppression of haematopoiesis

25
Q

drugs which might cause urinary retention

A

TCA, anticholinergics, opioids, NSAIDs, disopyramide

26
Q

pharmacological causes of polyuria

A

diuretics, Li, caffeine, EtOH

27
Q

SE of a-blockers

A

postural hypotension, drowsiness, dyspepsia, cough

28
Q

a-blockers are mainly used in the Rx of

A

BPH, HTN

29
Q

a-blocker examples

A

doxazosin, tamsulosin

30
Q

B-blocker indications

A

angina, post-MI, HF, arrhythmias, HTN, thyrotoxicosis, migraine prophylaxis, anxiety

31
Q

B-blocker examples

A

atenolol, propranolol

32
Q

SE of B-blockers

A

bronchospasm, cold peripheries, fatigue, sleep disturbances (inc nightmares)

33
Q

B-blocker CI

A

uncontrolled HF, asthma, sick sinus S, concurent verapanil use (may precipitate severe bradycardia)

34
Q

drugs that cause gingival hyperplasia

A

phenytoin, ciclosporin, CaChB (esp nifedipine)

35
Q

chronic SE of phenytoin

A

hirsuitism, coarsening of facial features

36
Q

6 drugs which can exacerbate psoriasis

A

B-blockers, Li, antimalarials (chloroquine, hydroxychloroquine), NSAIDs, ACEi, infliximab

37
Q

3 drugs/classes CI in asthma

A

NSAIDs. B-blockers, adenosine

38
Q

Li toxicity features

A

coarse tremor, hyperreflexia, acute confusion, seizure, coma

39
Q

4 drugs to stop in renal failure

A

ABx (tetracycline, nitrofurantoin), NSAIDs, Li, metformin

40
Q

6 drug causes of SIADH

A

sulphonylureas, SSRIs, TCA, carbamazepine, vincristine, cyclophosphamide

41
Q

5 drugs/classes that increase K

A

ACEi, AG2RB, spironolactone, K-sparing diuretics, K supplements

Medicine (30 decks)

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