General medicine Flashcards
anti oxidants contain
beta carotene
beta carotene is CI in
smoking (increases L ca risk)
beta carotene is in
anti oxidants
P450 inducers
antiepileptics (phenytoin, carbamazepine), barbituates (phenobarbitone), rifanpicin, St John’s Wort, chronic EtOH intake, grisofulvin, smoking
P450i
ABx (ciprofloxacin, erythromycin), isoniasid, cimetidine, omeprazole, amiodarone, allopurinol, imidazoles (ketoconazole, fluconazole), SSRIs (fluoxetine, sertraline), ritonavir, Na valproate, acute EtOH intake, quinupristin
complex regional pain S
umbrella term for reflex sympathetic dystrophy + causalgia, neuro + related symptoms which occur following Sx/minor injury
types of complex regional pain S
CRS type I = > common, no demonstrable lesion to a major n
CRS type II = there is a lesion to a major n
features of complex regional pain S
progressive, disproportionate symptoms to the original injury/Sx, allodynia, T’c + skin colour changes, oedema, sweating, motor dysfunction
management of complex regional pain S
early PT, neuropathic analgesia, refer to pain team
sympathetic dystrophy
old term for complec regional pain S
causalgia
severe burning pain in a limb caused by injury to a peripheral n
allodynia
central pain sensation following a non-painful stimulus
umbrella term for reflex sympathetic dystrophy + causalgia, neuro + related symptoms which occur following Sx/minor injury
complex regional pain S
progressive, disproportionate symptoms to the original injury/Sx, allodynia, T’c + skin colour changes, oedema, sweating, motor dysfunction are symptoms of
complex regional pain S
old term for complec regional pain S
sympathetic dystrophy
severe burning pain in a limb caused by injury to a peripheral n
causalgia
central pain sensation following a non-painful stimulus
allodynia
buproprion is CI in
epilepsy
buproprion is used in
smoking cessation
first line for smoking cessation
nicotine relacement therapy: varenicline or buproprion
varenicline should be started
1/52 before PT target stop date
duration of varenicline treatment
12/52
SE of varenicline
N, headache, insomnia, abnormal dreams
varenicline is CI in
pregnancy, breast feeding
buproprion should be started
1-2/52 before target stop date
buproprion is CI in
epilepsy, pregnancy, breast feeding, eating disorder
smoking cessation interventinos in pregnant womet
CBT, motivational interviewing, structured self-help
drug to start 1/52 before PT target stop smoking date
varenicline
drug to start 1-2/52 before target stop smoking date
buproprion
causes of massive splenomegaly
myelofibrosis, CML, visceral leishmaniasis, malaria, Gaucher’s S
myelofibrosis, CML, visceral leishmaniasis, malaria, Gaucher’s S are all causes of
massive splenomegaly
