General medicine

Question 1

anti oxidants contain

Answer 1

beta carotene

Question 2

beta carotene is CI in

Answer 2

smoking (increases L ca risk)

Question 3

beta carotene is in

Answer 3

anti oxidants

Question 4

P450 inducers

Answer 4

antiepileptics (phenytoin, carbamazepine), barbituates (phenobarbitone), rifanpicin, St John’s Wort, chronic EtOH intake, grisofulvin, smoking

Question 5

P450i

Answer 5

ABx (ciprofloxacin, erythromycin), isoniasid, cimetidine, omeprazole, amiodarone, allopurinol, imidazoles (ketoconazole, fluconazole), SSRIs (fluoxetine, sertraline), ritonavir, Na valproate, acute EtOH intake, quinupristin

Question 6

complex regional pain S

Answer 6

umbrella term for reflex sympathetic dystrophy + causalgia, neuro + related symptoms which occur following Sx/minor injury

Question 7

types of complex regional pain S

Answer 7

CRS type I = > common, no demonstrable lesion to a major n

CRS type II = there is a lesion to a major n

Question 8

features of complex regional pain S

Answer 8

progressive, disproportionate symptoms to the original injury/Sx, allodynia, T’c + skin colour changes, oedema, sweating, motor dysfunction

Question 9

management of complex regional pain S

Answer 9

early PT, neuropathic analgesia, refer to pain team

Question 10

sympathetic dystrophy

Answer 10

old term for complec regional pain S

Question 11

causalgia

Answer 11

severe burning pain in a limb caused by injury to a peripheral n

Question 12

allodynia

Answer 12

central pain sensation following a non-painful stimulus

Question 13

umbrella term for reflex sympathetic dystrophy + causalgia, neuro + related symptoms which occur following Sx/minor injury

Answer 13

complex regional pain S

Question 14

progressive, disproportionate symptoms to the original injury/Sx, allodynia, T’c + skin colour changes, oedema, sweating, motor dysfunction are symptoms of

Answer 14

complex regional pain S

Question 15

old term for complec regional pain S

Answer 15

sympathetic dystrophy

Question 16

severe burning pain in a limb caused by injury to a peripheral n

Answer 16

causalgia

Question 17

central pain sensation following a non-painful stimulus

Answer 17

allodynia

Question 18

buproprion is CI in

Answer 18

epilepsy

Question 19

buproprion is used in

Answer 19

smoking cessation

Question 20

first line for smoking cessation

Answer 20

nicotine relacement therapy: varenicline or buproprion

Question 21

varenicline should be started

Answer 21

1/52 before PT target stop date

Question 22

duration of varenicline treatment

Answer 22

12/52

Question 23

SE of varenicline

Answer 23

N, headache, insomnia, abnormal dreams

Question 24

varenicline is CI in

Answer 24

pregnancy, breast feeding

Question 25

buproprion should be started

Answer 25

1-2/52 before target stop date

Question 26

buproprion is CI in

Answer 26

epilepsy, pregnancy, breast feeding, eating disorder

Question 27

smoking cessation interventinos in pregnant womet

Answer 27

CBT, motivational interviewing, structured self-help

Question 28

drug to start 1/52 before PT target stop smoking date

Answer 28

varenicline

Question 29

drug to start 1-2/52 before target stop smoking date

Answer 29

buproprion

Question 30

causes of massive splenomegaly

Answer 30

myelofibrosis, CML, visceral leishmaniasis, malaria, Gaucher’s S

Question 31

myelofibrosis, CML, visceral leishmaniasis, malaria, Gaucher’s S are all causes of

Answer 31

massive splenomegaly